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Drug Details

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Name:Fluormethylprednisolone
PubChem ID:5743
Pathway:Show KEGG pathways
InChI:InChI=1/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1
SMILES:C[C@@H]1(C[C@H]2([C@@H]3(CCC4=CC(C=C[C@]4(C)[C@@]3([C@@H](C[C@]2(C)[C@@]1(C(CO)=O)O)O)F)=O)))

Properties:
Formula:C22H29FO5Atoms:32
Molecular Weight:392.461Rotatable Bonds:2
H-bond Acceptors:6H-bond Donors:0
logP:1.8957
Targets:
NameUniprot IDSourceReferencesInteraction
Androgen receptorANDR_HUMANBindingDB-shows
Annexin A1ANXA1_HUMANSuperTarget-shows
Arachidonate 5-lipoxygenaseLOX5_RATBindingDB-shows
Cholesterol 7-alpha-monooxygenaseCP7A1_HUMANSuperCypPMID 8180117shows
Cytochrome P450 11B1, mitochondrialC11B1_HUMANSuperCypPMID 8386113shows
Cytochrome P450 19A1CP19A_HUMANSuperCypPMID 15589976shows
Cytochrome P450 1A1CP1A1_HUMANSuperCypPMID 15620718shows
Cytochrome P450 1B1CP1B1_HUMANSuperCypPMID 11286621shows
Cytochrome P450 2A6CP2A6_HUMANSuperCypPMID 8313838shows
Cytochrome P450 2B6CP2B6_HUMANSuperCypPMID 11286621shows
Cytochrome P450 2C19CP2CJ_HUMANSuperCypPMID 12869636shows
Cytochrome P450 2C8CP2C8_HUMANSuperCypPMID 11181490shows
Cytochrome P450 2C9CP2C9_HUMANSuperCypPMID 11181490shows
Cytochrome P450 2D6CP2D6_HUMANSuperCyp-shows
Cytochrome P450 2E1CP2E1_HUMANSuperCypPMID 9207195shows
Cytochrome P450 3A4CP3A4_HUMANSuperCypPMID 9337077shows
Cytochrome P450 3A43CP343_HUMANSuperCypPMID 12679136shows
Cytochrome P450 3A5CP3A5_HUMANSuperCyp-shows
Cytochrome P450 3A7CP3A7_HUMANSuperCypPMID 17207564shows
Cytochrome P450 4A11CP4AB_HUMANSuperCypPMID 10773044shows
Fatty acid-binding protein, liverFABPL_RATBindingDB-shows
Glucocorticoid receptorGCR_HUMANSuperTarget-shows
Mineralocorticoid receptorMCR_HUMANBindingDB-shows
Multidrug resistance protein 1MDR1_HUMANBindingDB-shows
Nitric oxide synthase, inducibleNOS2_HUMANDrugBank-shows
Nuclear factor NF-kappa-B p100 subunitNFKB2_HUMANSuperTarget-shows
Nuclear factor NF-kappa-B p105 subunitNFKB1_HUMANSuperTarget-shows
Nuclear receptor subfamily 0 group B member 1NR0B1_HUMANDrugBank-shows
Phospholipase A2, major isoenzymePA21B_PIGBindingDB-shows
Progesterone receptorPRGR_HUMANBindingDB-shows
Prostaglandin G/H synthase 2PGH2_SHEEPBindingDB-shows
Steroid 17-alpha-hydroxylase/17,20 lyaseCP17A_HUMANSuperCypPMID 8385739shows
Sterol 26-hydroxylase, mitochondrialCP27A_HUMANSuperCypPMID 12597773shows
Stromal cell-derived factor 1SDF1_HUMANDrugBank-shows
Transcription factor p65TF65_HUMANSuperTargetPMID 11395507shows
Synonyms:
(11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,
(11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
(11beta,16alpha)-9-Fluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione labeled with tritium
(3H)-Dexamethasone
(3H)-Dexamethasone (labeled with tritium)
(8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
.delta.(sup 1)-9-.alpha.-Fluoro-16-.alpha.-methylcortisol
.gamma.corten
1-Dehydro-16-alpha-methyl-9-alpha-fluorohydrocortisone
1-Dehydro-16.alpha.-methyl-9.alpha.-fluorohydrocortisone
1-Dehydro-16alpha-methyl-9alpha-fluorohydrocortisone
137098-19-2
16-.alpha.-Methyl-9-.alpha.-fluoro-1,4-pregnadiene-11-.beta.,17-.alpha.,21-triol-3,20-dione
16-alpha-Methyl-9-alpha-fluoro-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione
16-alpha-Methyl-9-alpha-fluoro-1-dehydrocortisol
16-alpha-Methyl-9-alpha-fluoro-11-beta,17-alpha,21-trihydroxypregna-1,4-diene-3,20-dione
16-alpha-Methyl-9-alpha-fluoro-delta(sup 1)-hydrocortisone
16-alpha-Methyl-9-alpha-fluoro-delta1-hydrocortisone
16-alpha-Methyl-9-alpha-fluoroprednisolone
16.alpha.-Methyl-9.alpha.-fluoro-.delta.(sup1)-hydrocortisone
16.alpha.-Methyl-9.alpha.-fluoro-1-dehydrocortisol
16.alpha.-Methyl-9.alpha.-fluoro-11.beta.-17.alpha.-21-trihydroxypregna-1,4-diene-3,20-dione
16.alpha.-Methyl-9.alpha.-fluoroprednisolone
16alpha-Methyl-9alpha-fluoro-1-dehydrocortisol
16alpha-Methyl-9alpha-fluoro-delta(sup 1)-hydrocortisone
16alpha-Methyl-9alpha-fluoroprednisolone
23495-06-9
31375_FLUKA
4-alpha-Fluoro-16-alpha-methyl-11-beta,17,21-trihydroxypregna-1,4-diene-3,20-dione
4.alpha.-Fluoro-16.alpha.-methyl-11.beta.-17,21-trihydroxypregna-1,4-diene-3,20-dione
46165_FLUKA
46165_RIEDEL
50-02-2
8054-59-9
9-alpha-Fluoro-16-alpha-methyl-1,4-pregnadiene-11-beta,17-alpha,21-triol-3,20-dione
9-alpha-Fluoro-16-alpha-methylprednisolone
9-Fluoro-11-beta,17,21-trihydroxy-16-alpha-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione
9-Fluoro-11beta,17,21-trihydroxy-16alpha-methylpregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-11.beta.-17.alpha.- 21-trihydroxy-16.alpha.-methylpregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-methyl-1,4-pregnadiene-11.beta.-17-.alpha.-21-triol-3,20-dione
9.alpha.-Fluoro-16.alpha.-methyl-11.beta.,17.alpha.,21.beta.-trihydroxy-pregna-1,4-diene-3,20-dione
9.alpha.-Fluoro-16.alpha.-methylprednisolone
9A-FLUORO-16BETA-METHYLPREDNISOLONE
9alpha-Fluoro-16alpha-methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
9alpha-Fluoro-16alpha-methylprednisolone
Aeroseb-D
Aeroseb-Dex
AI3-50934
Anaflogistico
Aphtasolon
Auxiron
Azimycin (Veterinary)
Azium
Azium (Veterinary)
Bisu DS
BSPBio_000995
C15643
C22H29FO5
Calonat
CCRIS 7067
CHEBI:41879
component of Dronactin
Corson
Corsone
Cortisumman
D00292
D1756_SIGMA
D4902_SIGMA
D6645_SIGMA
D8893_SIGMA
D9184_SIGMA
DB01234
Decacortin
Decaderm
Decadron
Decadron (TN)
Decadron Tablets, Elixir
Decadron-LA
Decagel
Decalix
Decasone
Decaspray
Dectancyl
Dekacort
delta(sup 1)-9-alpha-Fluoro-16-alpha-methylcortisol
delta1-9alpha-Fluoro-16alpha-methylcortisol
Deltafluorene
Dergramin
Deronil
Desadrene
Desametasone
Desametasone [DCIT]
Desamethasone
Desameton
Deseronil
DEX
Dex-ide
Dexa Mamallet
Dexa-Cortidelt
Dexa-Cortisyl
Dexa-Scheroson
Dexa-sine
Dexacen-4
Dexacidin
Dexacort
Dexacortal
Dexacortin
Dexadeltone
Dexafarma
Dexair
Dexalona
Dexametasona
Dexametasona [INN-Spanish]
Dexameth
Dexamethansone
Dexamethasone
Dexamethasone (JP15/USP/INN)
Dexamethasone Acetate
Dexamethasone alcohol
Dexamethasone Base
DEXAMETHASONE INTENSOL
Dexamethasone sodium phosphate
Dexamethasone [BAN:INN:JAN]
Dexamethasone [INN:BAN:JAN]
Dexamethasonum
Dexamethasonum [INN-Latin]
Dexamethazone
Dexapolcort
Dexapos
Dexaprol
Dexason
Dexasone
DEXASPORIN
Dexinolon
Dexinoral
Dexone
DEXONE 0.5
DEXONE 0.75
DEXONE 1.5
DEXONE 4
Dextelan
Dezone
Dinormon
DRG-0013
DXM
DXMS
EINECS 200-003-9
Fluormethylprednisolone
Fluormone
Fluorocort
Fortecortin
Fulvidex (Veterinary)
Gammacorten
Hexadecadrol
Hexadrol
Hexadrol Elixir
Hexadrol Tablets
HL-Dex
HSDB 3053
Isopto-Dex
Lokalison F
Loverine
LS-7300
Luxazone
Maxidex
Maxidex (TN)
Maxitrol
Mediamethasone
Methylfluorprednisolone
Mexidex
Millicorten
Mixture Name
MK 125
MLS001055412
MLS001332507
MLS001332508
MolMap_000018
MYMETHASONE
Naquasone (Veterinary)
NCGC00091019-01
NCGC00091019-02
NCGC00091019-03
NCGC00091019-04
NCGC00091019-05
nchembio809-comp2
NCI60_003067
NEOMYCIN AND POLYMYXIN B SULFATES AND DEXAMETHASONE
NSC 34521
NSC34521
Ocu-trol
Oradexon
Pet Derm III
Policort
Prednisolon F
Prednisolone F
Prednisolone, 9.alpha.-fluoro-16.alpha.-methyl-
Prednisolone, 9alpha-fluoro-16alpha-methyl-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11.beta.,16.alpha.)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, (11beta,16alpha)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11,17,21-trihydroxy-16-methyl-, labeled with tritium, (11beta,16alpha)-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11.beta.,17,21-trihydroxy-16.alpha.-methyl-
Pregna-1,4-diene-3,20-dione, 9-fluoro-11beta,17,21-trihydroxy-16alpha-methyl-
ProDex
SGCUT00126
SK-Dexamethasone
SMP1_000092
SMR000857119
SMR001227192
Spectrum5_002019
Spoloven
ST5307091
Sunia Sol D
Superprednol
TL8003317
Tobradex
TOBRAMYCIN AND DEXAMETHASONE
to_000038
Tresaderm (Veterinary)
Turbinaire
Visumetazone
WLN: L E5 B666 OV KU MUTJ A1 BF CQ E1 FV1Q FQ G1
ZINC03875332
ATC-Codes: