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Name:BICALUTAMIDE
PubChem ID:56069
Pathway:Show KEGG pathways
InChI:InChI=1/C18H14F4N2O4S/c1-17(26,10-29(27,28)14-6-3-12(19)4-7-14)16(25)24-13-5-2-11(9-23)15(8-13)18(20,21)22/h2-8,26H,10H2,1H3,(H,24,25)/t17-/m0/s1/f/h24H
SMILES:C[C@](CS(c1ccc(cc1)F)(=O)=O)(C(Nc1ccc(C#N)c(c1)C(F)(F)F)=O)O

Properties:
Formula:C18H14F4N2O4SAtoms:29
Molecular Weight:430.373Rotatable Bonds:7
H-bond Acceptors:10H-bond Donors:0
logP:4.03338
Targets:
Synonyms:
(+)-4'-cyano-alpha,alpha,alpha-trifluoro-3-((p-fluorophenyl)sulfonyl)-2-methyl-m-lactotoluidide
(+-)-4'-Cyano-alpha,alpha,alpha-trifluoro-3-((p-fluorophenyl)sulfonyl)-2-methyl-m-lactotoluidide
(2R)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methylpropanamide
(2R)-N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-3-[(4-FLUOROPHENYL)SULFONYL]-2-
(2R)-N-[4-CYANO-3-(TRIFLUOROMETHYL)PHENYL]-3-[(4-FLUOROPHENYL)SULFONYL]-2-HYDROXY-2-METHYLPROPANAMIDE
(R)-Bicalutamide
1z95
90357-06-5
BICALUTAMIDE
Bicalutamide [USAN:BAN:INN]
BRN 5364666
Casodex
CHEBI:3090
DB01128
DB02932
ICI 176334
NCGC00167487-01
Propanamide, N-(4-cyano-3-(trifluoromethyl)phenyl)-3-((4-fluorophenyl)sulfonyl)-2-hydroxy-2-methyl-, (+-)-
R-BICALUTAMIDE
STOCK6S-47735
ZINC00538564
ATC-Codes:
Side-Effects:
Side-EffectFrequency
urticaria0.0010
pulmonary fibrosis0.0010
hypersensitivity0.0010
interstitial lung disease0.0010
angioneurotic edema0.0010
interstitial pneumonitis0.0010
pneumonia0
pleural effusion0
pharyngitis0
periodontal abscess0
pelvic pain0
infection0
pruritus0
rhinitis0
sinusitis0
skin ulcer0
cerebrovascular accident0
sweating0
syncope0
paresthesia0
pain0
influenza0
jaundice0
kidney calculus0
leg cramps0
lung disorder0
breast pain0
mediastinal disorders0
melena0
myocardial infarction0
nausea0
tumor0
nervousness0
neutropenia0
nocturia0
thrombocytopenia0
urinary incontinence0
urinary tract infection0
dry skin0
deep thrombophlebitis0
iron deficiency anemia0
myalgia0
sepsis0
breast tenderness0
rectal hemorrhage0
bradycardia0
laboratory test abnormal0
neuropathy0
urinary frequency0
skin carcinoma0
cerebral ischemia0
insomnia0
sgot increased0
alkaline phosphatase increased0
hepatic failure0
abnormal vision0
vomiting0
weight gain0
weight loss0
dry mouth0
urinary retention0
chills0
urinary urgency0
peripheral edema0
cataract0
neck rigidity0
liver function tests abnormal0
bone pain0
allergic reaction0
abdominal pain0
neck pain0
chest pain0
confusion0
conjunctivitis0
constipation0
constitutional symptoms0
coronary artery disease0
cough0
cyst0
decreased libido0
dysphagia0
dehydration0
diabetes mellitus0
diarrhea0
carcinoma0
cancer0
bronchitis0
alopecia0
anemia0
hypochromic anemia0
angina pectoris0
anorexia0
anxiety0
arrhythmia0
arthritis0
asthenia0
asthma0
atrial fibrillation0
back pain0
balanitis0
breast disorders0
dizziness0
somnolence0
dyspepsia0
heart failure0
congestive heart failure0
hematuria0
hemorrhage0
hernia0
herpes zoster0
hirsutism0
hot flashes0
hydronephrosis0
hypercalcemia0
hypercholesterolemia0
hyperglycemia0
hypertension0
hypoglycemia0
cardiac arrest0
headache0
gynecomastia0
dyspnea0
dysuria0
ecchymosis0
edema0
eosinophilia0
epistaxis0
rash0
fatigue0
fever0
flatulence0
flushing0
pathological fracture0
gastritis0
gout0
impotence0