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Drug Details

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Name:Isotretinoin
PubChem ID:5538
Pathway:Show KEGG pathways
InChI:InChI=1S/C20H28O2/c1-15(8-6-9-16(2)14-19(21)22)11-12-18-17(3)10-7-13-20(18,4)5/h6,8-9,11-12,14H,7,10,13H2,1-5H3,(H,21,22)
SMILES:-

Properties:
Formula:C20H28O2Atoms:22
Molecular Weight:300.435Rotatable Bonds:5
H-bond Acceptors:2H-bond Donors:0
logP:5.6026
Targets:
Synonyms:
3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid
3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic
3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid
5300-03-8
AC1L1KKH
All Trans Retinoic Acid
All Trans-Retinoic Acid
ATRA
beta-Retinoic Acid
Bio1_000106
Bio1_000108
Bio1_000110
Bio1_000595
Bio1_000597
Bio1_000599
Bio1_001084
Bio1_001086
Bio1_001088
Bio2_000051
Bio2_000215
Bio2_000220
Bio2_000531
Bio2_000695
Bio2_000700
CBiol_001820
CBiol_001822
CBiol_001824
CHEBI:26536
CHEMBL1235644
CID5538
DB00755
DB00982
DivK1c_000903
DivK1c_006792
Isotretinoin
Isotretinoin Retinoic acid
KBio1_000903
KBio1_001736
KBio2_000051
KBio2_000215
KBio2_000220
KBio2_002156
KBio2_002619
KBio2_002783
KBio2_002788
KBio2_004724
KBio2_005187
KBio2_005351
KBio2_005356
KBio2_007292
KBio3_000101
KBio3_000102
KBio3_000429
KBio3_000430
KBio3_000439
KBio3_000440
KBio3_002847
KBioGR_000051
KBioGR_000215
KBioGR_000220
KBioGR_001362
KBioSS_000051
KBioSS_000215
KBioSS_000220
KBioSS_002156
NCI60_000538
NINDS_000903
Prestwick0_000256
Prestwick0_000257
Prestwick1_000256
Prestwick1_000257
retinoic acid
Retionic Acid
SPBio_002165
SPBio_002291
SPBio_002293
SpecPlus_000696
Spectrum2_001983
Spectrum3_001793
Spectrum4_000901
Spectrum_001676
Tretinoin
ATC-Codes:
Side-Effects:
Side-EffectFrequency
pain0.0010
seborrhea0.0010
seizures0.0010
dry skin0.0010
sweating0.0010
syncope0.0010
tachycardia0.0010
tendonitis0.0010
thrombocytopenia0.0010
rhabdomyolysis0.0010
psychosis0.0010
palpitation0.0010
pancreatitis0.0010
weakness0.0010
paresthesias0.0010
paronychia0.0010
proteinuria0.0010
pruritus0.0010
pseudotumor cerebri0.0010
tinnitus0.0010
hearing impairment0.0010
erythema0.0010
esophageal ulceration0.0010
hyperpigmentation0.0010
hypopigmentation0.0010
malaise0.0010
myalgia0.0010
xanthomas0.0010
dry eyes0.0010
lymphadenopathy0.0010
hyperuricemia0.0010
allergic vasculitis0.0010
urticaria0.0010
insomnia0.0010
voice alteration0.0010
weight loss0.0010
dry mouth0.0010
photophobia0.0010
pyogenic granuloma0.0010
cataracts0.0010
acne0.0010
optic neuritis0.0010
agranulocytosis0.0010
corneal opacities0.0010
dermatitis0.0010
diabetes0.0010
dizziness0.0010
drowsiness0.0010
eczema0.0010
edema0.0010
epistaxis0.0010
conjunctivitis0.0010
colitis0.0010
alopecia0.0010
anemia0.0010
joint pain0.0010
arthritis0.0010
asthma0.0010
back pain0.0010
eyelid inflammation0.0010
bronchospasms0.0010
esophagitis0.0010
rash0.0010
fatigue0.0010
hypersensitivity0.0010
hypertriglyceridemia0.0010
infections0.0010
inflammatory bowel disease0.0010
keratitis0.0010
allergic reactions0.0010
nausea0.0010
nervousness0.0010
hyperostosis0.0010
hoarseness0.0010
flushing0.0010
glomerulonephritis0.0010
headache0.0010
hematuria0.0010
bleeding0.0010
hepatitis0.0010
herpes simplex0.0010
hirsutism0.0010
neutropenia0.0010
stroke0.00088
vasculitis0.00088
thrombocytosis0.0
ulceration0.0
myocardial infarction0.0
ischemia0
nasal congestion0
convulsions0
exfoliative dermatitis0
swelling0
peripheral edema0
tremor0
phlebitis0
anorexia0
fasciitis0
pericardial effusion0
dementia0
blurred vision0
pericarditis0
hypothermia0
clotting0
cardiac murmur0
cardiomegaly0
heart failure0
congestive heart failure0
musculoskeletal pain0
stomatitis0
abnormal gait0
liver disease0
retinal hemorrhage0
skin irritation0
urinary frequency0
cardiac arrest0
dysarthria0
erythema nodosum0
acute pancreatitis0
osteitis0
vomiting0
anxiety0
ophthalmoplegia0
generalized pain0
cystitis0
loss of consciousness0
agnosia0
hallucinations0
spinal cord disease0
hypotension0
emotional lability0
increased sweating0
abnormal vision0
dyspnea0
constitutional symptoms0
arrhythmia0
blistering0
acidosis0
lightheadedness0
gastritis0
wheezing0
dehydration0
dyspepsia0
abdominal pain0
cerebral hemorrhage0
hypoxia0
unconsciousness0
bleeding diathesis0
bone pain0
chest pain0
renal failure0
renal insufficiency0
puncture0
cardiomyopathy0
hemiplegia0
agitation0
visual field defect0
duodenal ulcer0
pleural effusion0
septicemia0
abdominal distention0
hypertension0
urinary tract infection0
ear pain0
esr increased0
dysphagia0
forgetful0
rectal hemorrhage0
myocarditis0
fever0
hypercalcemia0
cellulitis0
myositis0
gastrointestinal hemorrhage0
confusion0
ascites0
photosensitivity0
numbness0
moniliasis0
hyperlipidemia0
hypercholesterolemia0
hypervitaminosis0
papilledema0
embolism0
coma0
lung disorder0
shock0
pulmonary infiltration0
gout0
weight gain0
pulmonary edema0
leukocytosis0
encephalopathy0
pneumonia0
sinusitis0
aphasia0
cough0
flatulence0
nail disorder0
facial paralysis0
asthenia0
pharyngitis0
diarrhea0
dysuria0
flank pain0
constipation0