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Drug Details

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Name:Methazolastone
PubChem ID:5394
Pathway:Show KEGG pathways
InChI:InChI=1/C6H6N6O2/c1-11-6(14)12-2-8-3(4(7)13)5(12)9-10-11/h2H,1H3,(H2,7,13)/f/h7H2
SMILES:Cn1c(n2cnc(C(N)=O)c2nn1)=O

Properties:
Formula:C6H6N6O2Atoms:14
Molecular Weight:194.151Rotatable Bonds:1
H-bond Acceptors:6H-bond Donors:0
logP:-1.3778
Targets:
Synonyms:
3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-1,2,3,5-tetrazine-8-carboxamide
3,4-Dihydro-3-methyl-4-oxoimidazo(5,1-d)-as-tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide
3-Methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetraazine-8-carboxamide
3-methyl-4-oxo-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide
8-Carbamoyl-3-methylimidazo(5,1-d)-1,2,3,5-tetrazin-4(3H)-one
85622-93-1
AIDS-129717
AIDS129717
BRN 5547136
C047246
C6H6N6O2
CCRG 81045
CCRG-81045
CCRIS 8996
CPD000466338
D06067
DB00853
Essex brand of temozolomide
Imidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide,
Imidazo(5,1-d)(1,2,3,5)tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-
Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3,4-dihydro-3-methyl-4-oxo-
LS-80558
M & B 39831
M&B 39831
M&B-39831
MB 39831
Methazolastone
MLS000759447
MLS001424028
NCGC00167429-01
NCGC00167429-02
NCI60_003316
NSC 362856
NSC-362856
NSC362856
SAM001246636
Sch 52365
Sch-52365
Schering brand of temozolomide
Schering-Plough brand of temozolomide
SMR000466338
STOCK6S-53841
Temodal
Temodal (TN)
Temodar
Temozolamide
Temozolodida [Spanish]
Temozolomide
Temozolomide (JAN/USAN/INN)
Temozolomide [BAN:INN]
Temozolomide [INN:BAN]
Temozolomidum [Latin]
TL8005593
ZINC01482184
{Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide,} 3, 4-dihydro-3-methyl-4-oxo-
ATC-Codes:
Side-Effects:
Side-EffectFrequency
lymphopenia0.546053
confusion0.0
insomnia0.0
weight increase0.0
infection viral0.0
urinary tract infection0.0
upper respiratory tract infection0.0
sinusitis0.0
pharyngitis0.0
rash0.0
diplopia0.0
coughing0.0
convulsions0.0
pancytopenia0
palpitations0
peripheral edema0
petechiae0
ischemia0
dyspepsia0
dermatitis0
dysphagia0
anemia0
thrombophlebitis0
anorexia0
sensory disturbance0
somnolence0
infection0
connective tissue disorders0
erythema multiforme0
constitutional symptoms0
heart disease0
urinary frequency0
clotting0
weakness0
aphasia0
paresthesia0
toxic epidermal necrolysis0
deafness0
cerebral hemorrhage0
stomatitis0
dry skin0
abnormal gait0
vascular disorders0
sgot increased0
cerebral ischemia0
influenza0
mediastinal disorders0
constipation0
amnesia0
anxiety0
breast disorders0
breast pain0
dry eyes0
abnormal pigmentation0
neuropathy0
myalgia0
arthralgia0
hallucinations0
increased sweating0
dysuria0
headache0
behavior disorder0
emotional lability0
apathy0
vomiting0
hearing loss0
vaginal hemorrhage0
glioma0
nasal congestion0
otitis media0
amenorrhea0
thrombocytopenia0
hemorrhage0
status epilepticus0
neutropenia0
dehydration0
abdominal distention0
myelogenous leukemia0
abdominal pain0
dysphasia0
dyspnea0
abnormal vision0
memory impairment0
myelodysplastic syndrome0
visual field defect0
pain0
fecal incontinence0
herpes simplex0
tooth disorder0
nausea0
pneumocystis carinii pneumonia0
alopecia0
photosensitivity0
menorrhagia0
musculoskeletal pain0
hypokalemia0
deep vein thrombosis0
flushing0
infertility0
cancer0
hemiplegia0
gastroenteritis0
erythema0
agitation0
back pain0
ear pain0
hyperacusis0
fever0
impotence0
stevens - johnson syndrome0
urinary incontinence0
hypertension0
pruritus0
eye pain0
transient ischemic attack0
dry mouth0
aplastic anemia0
leukopenia0
pneumonia0
concentration impaired0
seizures0
moniliasis0
intracranial hemorrhage0
myopathy0
herpes zoster0
anaphylaxis0
pulmonary embolism0
embolism0
tremor0
hemiparesis0
hot flashes0
peripheral neuropathy0
malaise0
allergic reaction0
bronchitis0
tinnitus0
diarrhea0
blurred vision0
purpura0
hyperesthesia0
alkaline phosphatase increased0
hyperglycemia0
hemorrhoids0
edema0
dizziness0
ataxia0
vaginitis0
fatigue0
endocrine disorders0
muscle weakness0
asthenia0
vertigo0
weight loss0