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Drug Details

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Name:Rifampicinum
PubChem ID:5381226
Pathway:Show KEGG pathways
InChI:InChI=1/C43H58N4O12/c1-21-12-11-13-22(2)42(55)45-33-28(20-44-47-17-15-46(9)16-18-47)37(52)30-31(38(33)53)36(51)26(6)40-32(30)41(54)43(8,59-40)57-19-14-29(56-10)23(3)39(58-27(7)48)25(5)35(50)24(4)34(21)49/h11-14,19-21,23-25,29,34-35,39,44,49-51,53H,15-18H2,1-10H3,(H,45,55)/b12-11+,19-14+,22-13-,28-20+/t21-,23+,24+,25+,29-,34-,35+,39+,43-/m0/s1/f/h45H
SMILES:C[C@H]1(C(=C(/[H])C(/[H])=C(/C)C(NC=2\C(=C(/[H])NN3CCN(C)CC3)C(c3c(c(c(C)c4c3C([C@](C)(OC(=C(/[H])[C@H]([C@H](C)[C@@H]([C@@H](C)[C@H]([C@H](C)[C@H]1O)O)OC(C)=O)OC)\[H])O4)=O)O)C2O)=O)=O)\[H])

Properties:
Formula:C43H58N4O12Atoms:73
Molecular Weight:822.94Rotatable Bonds:5
H-bond Acceptors:16H-bond Donors:0
logP:4.0217
Targets:
Synonyms:
13292-46-1
2,7-(Epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-(N-(4-methyl-1-piperazinyl)formimidoyl)-, 21-acetate (8CI)
2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione,
2,7-(Epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione, 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-, 21-acetate
2,7-(epoxy[1,11,13]pentadecatrienoimino)naphtho[2,1-b]furan-1,11(2H)-dione, 21-(acetyloxy)-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[(E)-[(4-methyl-1-piperazinyl)imino]meth
3-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
3-(4-Methylpiperazinyliminomethyl)-rifamycin SV
3-(4-Methylpiperazinyliminomethyl)rifamycin SV
3-([(4-Methyl-1-piperazinyl)imino]methyl)rifamycin SV
3-[(4-Methyl-1-piperazinyl)iminomethyl]rifamycin SV
3-[[(4-Methyl-1-piperazinyl)imino]-methyl]rifamycin
46713_FLUKA
46713_RIEDEL
5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-(N-(4-methyl-1-piperazinyl)formimidoyl)-2,7-(epoxypentadeca(1,11,13)trienimino)naphtho(2,1-b)furan-1,11(2H)-dione 21-acetate
5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-, 21-acetate
8-(((4-Methyl-1-piperazinyl)imino)methyl)rifamycin SV
8-(4-Methylpiperazinyliminomethyl) rifamycin SV
8-[[(4-Methyl-1-piperazinyl)imino[methyl]rifamycin
8-[[(4-Methyl-1-piperazinyl)imino]methyl]rifamycin sv
8-[[(4-Methylpiperazinyl)imino]methyl]rifamycin sv
83907_FLUKA
83907_SIGMA
8CI)
Abrifam
AIDS-007228
AIDS-032285
AIDS-088820
AIDS007228
AIDS032285
AIDS088820
Archidyn
Arficin
Arzide
Ba 41166
Ba 41166/E
BA-41166E
Benemicin
C06688
CCRIS 551
CHEBI:28077
D00211
Dione 21-acetate
Doloresum
DRG-0109
EINECS 236-312-0
Eremfat
Famcin
Fenampicin
HMS1569J11
HSDB 3181
L-5103
L-5103 Lepetit
NSC 113926
NSC-113926
NSC113926
Piperine & Rifampicin
Prestwick_833
R-Cin
R/AMP
R3501_SIAL
R3501_SIGMA
R5777_SIGMA
R7382_SIGMA
RAMP
Reserpine & Rifampicin
Rf
RFP
RIF
Rifa
Rifadin
Rifadin (TN)
Rifadin I.V.
Rifadin, Rimactane, Rifampicin, Rifampin
Rifadine
Rifagen
Rifaldazin
Rifaldazine
Rifaldin
Rifam
Rifamor
Rifampicin
Rifampicin & EEP
Rifampicin & Propolis
Rifampicin (JP15/INN)
Rifampicin (JP16/INN)
Rifampicin SV
Rifampicin [INN:BAN:JAN]
Rifampicina
Rifampicina [INN-Spanish]
Rifampicine
Rifampicine [French]
Rifampicinum
Rifampicinum [INN-Latin]
Rifampin
Rifampin & CRL8131
Rifampin (USP)
Rifampin [USAN]
Rifamsolin
Rifamycin AMP
Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-
Rifamycin, 3-[[(4-methyl-1-piperazinyl)imino]methyl]-
Rifaprodin
Rifater
Rifcin
Rifinah
Rifobac
Rifoldin
Rifoldine
Rifomycin SV, 8-(N-(4-methyl-1-piperazinyl)formidoyl)-
Rifomycin sv, 8-[N-(4-Methyl-1-piperazinyl)formidoyl]-
Riforal
Rimactan
Rimactane
Rimactane (TN)
Rimactazid
Rimactizid
Rimazid
RMP
S1764_Selleck
Sinerdol
Stereoisomer of 5,6,9,17,19,21-Hexahydroxy-23-methoxy-2,4,12,16,18,20,22-he@ptamethyl-8-[N-(4-methyl-1-piperazinyl)formimidoyl]-2,7-(epoxypentadeca[1,11,13]trienimino)naphtho[2,1-b]furan-1,11(2H)-dione 21-acetate
Tubocin
UNII-VJT6J7R4TR
WLN: V1 WQ A&1 E&1 E1UN- AT6N DNTJ D1
yl]-, (2S,12Z,14E,16S,17S,18R,19R,20R,21S,22R,23S,24E)-
ATC-Codes:
Side-Effects:
Side-EffectFrequency
lyell syndrome0.120000005
rash0.120000005
exfoliative dermatitis0.120000005
urticaria0.120000005
pruritus0.120000005
erythema0.120000005
hypersensitivity0.120000005
diarrhea0.09
nausea0.09
vomiting0.09
pain0.07333333
phlebitis0.055
edema0.055
arthralgia0.055
coughing0.045
hemoptysis0.045
chest pain0.045
pneumothorax0.045
angina0.045
palpitation0.045
tinnitus0.035
sweating0.035
coma0.035
headache0.035
vertigo0.035
paresthesia0.035
insomnia0.035
anxiety0.035
fever0.024999999
hepatitis0.01
jaundice0.01
anaphylaxis0
heartburn0
psychosis0
concentration impaired0
cerebral hemorrhage0
liver function tests abnormal0
endocrine disorders0
metrorrhagia0
hemoglobinuria0
fatigue0
anemia0
somnolence0
flushing0
shock0
acute tubular necrosis0
renal insufficiency0
eosinophilia0
glossodynia0
muscle cramps0
adrenal insufficiency0
conjunctivitis0
anorexia0
pseudomembranous colitis0
leukopenia0
enterocolitis0
interstitial nephritis0
purpura0
chills0
hematuria0
shortness of breath0
acute renal failure0
myopathy0
numbness0
erythema multiforme0
connective tissue disorders0
amenorrhea0
flatulence0
agranulocytosis0
bone pain0
hemolytic anemia0
ataxia0
dizziness0
wheezing0
muscle weakness0
stevens - johnson syndrome0
confusion0
thrombocytopenia0
vasculitis0