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Drug Details

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Name:DEXTROMETHORPHAN
PubChem ID:5360696
Pathway:Show KEGG pathways
InChI:InChI=1/C18H25NO/c1-19-10-9-18-8-4-3-5-15(18)17(19)11-13-6-7-14(20-2)12-16(13)18/h6-7,12,15,17H,3-5,8-11H2,1-2H3/t15-,17-,18-/m1/s1
SMILES:CN1CC[C@]23CCCC[C@H]2[C@@H]1(Cc1ccc(cc31)OC)

Properties:
Formula:C18H25NOAtoms:22
Molecular Weight:271.397Rotatable Bonds:1
H-bond Acceptors:2H-bond Donors:0
logP:3.3213
Targets:
NameUniprot IDSourceReferencesInteraction
Cholesterol 24-hydroxylaseCP46A_HUMANSuperCypPMID 14640697shows
Cytochrome P450Q6XP50_HUMANSuperTargetPMID 016124035shows
Cytochrome P450Q7Z448_HUMANSuperTargetPMID 009352574shows
Cytochrome P450Q86SK2_HUMANSuperTargetPMID 009352574shows
Cytochrome P450Q86SK3_HUMANSuperTargetPMID 009352574shows
Cytochrome P450 2B6CP2B6_HUMANSuperCypPMID 10760842shows
Cytochrome P450 2C19CP2CJ_HUMANSuperCypPMID 9113345shows
Cytochrome P450 2C8CP2C8_HUMANSuperCyp-shows
Cytochrome P450 2C9CP2C9_HUMANSuperCypPMID 9811160shows
Cytochrome P450 2D1CP2D1_RATPROMISCUOUSPMID 16621933shows
Cytochrome P450 2D6Q38LF9_HUMANPROMISCUOUSPMID 18362694shows
Cytochrome P450 2D6Q38LG0_HUMANPROMISCUOUSPMID 18362694shows
Cytochrome P450 2D6Q38LG2_HUMANPROMISCUOUSPMID 18362694shows
Cytochrome P450 2D6CP2D6_HUMANPROMISCUOUSPMID 18362694shows
Cytochrome P450 2E1CP2E1_HUMANSuperCyp-shows
Cytochrome P450 3A4CP3A4_HUMANPROMISCUOUSPMID 9390105shows
Cytochrome P450 3A5CP3A5_HUMANSuperCypPMID 8043020shows
Cytochrome P450 3A7CP3A7_HUMANSuperCypPMID 8043020shows
Cytochrome P450 CYP3A4Q9BZM0_HUMANSuperTargetPMID 009352574shows
Cytochrome P450 family 3 subfamily A polypeptide 4Q6GRK0_HUMANSuperTargetPMID 009352574shows
Cytochrome P450, family 2, subfamily D, polypeptide 6Q6NWU0_HUMANSuperTargetPMID 016124035shows
Cytochrome P450db1Q16804_HUMANSuperTargetPMID 016124035shows
Glutamate [NMDA] receptor subunit 3ANMD3A_HUMANSuperTargetPMID 9125411shows
Neuronal acetylcholine receptor subunit alpha-2ACHA2_HUMANSuperTarget-shows
Neuronal acetylcholine receptor subunit alpha-3ACHA3_HUMANSuperTarget-shows
Opioid receptor, sigma 1Q5T1J1_HUMANSuperTargetPMID 14691051shows
Sigma 1-type opioid receptorOPRS1_HUMANDrugBank-shows
Sodium-dependent serotonin transporterSC6A4_HUMANSuperTarget-shows
Synonyms:
(
( )-3-Methoxy-N-methylmorphinon
( )-cis-1,3,4,9,10,10a-Hexahydro-6-methoxy-11-methyl-2H-10,4alpha-iminoethanophenanthren
()-3-methoxy-17-methylmorphinan
(+)-3-Methoxy-17-methylmorphinan
(9alpha,13alpha,14alpha)-17-methyl-3-(methyloxy)morphinan
125-69-9
125-71-3
18046-32-7
18609-21-7
3-Methoxy-17-methyl-9alpha,13alpha,14alpha-morphinan
32062-10-5
4-21-00-01367 (Beilstein Handbook Reference)
6700-34-1
9-alpha,13-alpha,14-alpha-Morphinan, 3-methoxy-17-methyl-
9alpha,13alpha,14alpha-Morphinan, 3-methoxy-17-methyl-
9alpha,13alpha,14alpha-Morphinan, 3-methoxy-17-methyl- (8CI)
BA 2666
Benylin DM
BPBio1_000503
BRN 0088549
BSPBio_000457
C18H25NO
Canfodion
Cosylan
Cough-X
d-Methorphan
D03742
DELSYM
delta-Methorphan
Demorphan hydrobromide
Demorphine
Destrometerfano [DCIT]
DEX
Dextromethorfan [Czech]
DEXTROMETHORPHAN
Dextromethorphan (USP)
DEXTROMETHORPHAN POLISTIREX
Dextromethorphan [BAN:INN]
Dextromethorphan [USP:INN:BAN]
Dextromethorphane [INN-French]
Dextromethorphanum [INN-Latin]
Dextrometorfano [INN-Spanish]
Dextromorphan
DIMETANE-DX
Dormetan
EINECS 204-752-2
Hihustan M.
HSDB 3056
l-Methorphan
Levomethorphan
Lopac-D-2531
LS-91838
MLS000758303
Morphinan, 3-methoxy-17-methyl-, (9-alpha,13-alpha,14-alpha)-
Morphinan, 3-methoxy-17-methyl-, (9-alpha,13-alpha,14-alpha)- (9CI)
Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-
NCGC00015333-01
NCGC00015333-02
Prestwick0_000359
Prestwick1_000359
Prestwick2_000359
Prestwick3_000359
Racemethorphan
SMR000326694
SPBio_002378
ATC-Codes: