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Drug Details

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Name:Lovastatin
PubChem ID:53232
Pathway:Show KEGG pathways
InChI:InChI=1/C24H36O5/c1-5-15(3)24(27)29-21-11-14(2)10-17-7-6-16(4)20(23(17)21)9-8-19-12-18(25)13-22(26)28-19/h6-7,10,14-16,18-21,23,25H,5,8-9,11-13H2,1-4H3/t14-,15-,16-,18+,19+,20-,21-,23-/m0/s1
SMILES:CC[C@@H](C)C(=O)O[C@H]1(C[C@@H](C)(C=C2C=C[C@@H](C)[C@H](CC[C@@H]3(C[C@@H](CC(=O)O3)O))[C@@H]12))

Properties:
Formula:C24H36O5Atoms:37
Molecular Weight:404.54Rotatable Bonds:7
H-bond Acceptors:5H-bond Donors:0
logP:4.1955
Targets:
Synonyms:
(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-(2-(2R,4R)-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl (S)-2-methyl-butyrate
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]et
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl (2S)-2-methylbutanoate
(1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))-2-Methylbutanoic acid 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
(2S)-2-Methylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
(S)-2-Methyl-butyric acid (1S,3R,7S,8S,8aR)-8-[2-((3R,5R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl ester
(S)-2-Methylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
1,2,6,7,8,8a-Hexahydro-beta,delta-dihydroxy-2,6-dimethyl-8-(2-methyl-1-oxobutyoxy)-1-naphthaleneheptanoic acid delta-lactone
1cqp
2-Methyl-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl]-1-naphthalenyl ester butanoic acid
2beta,6alpha-Dimethyl-8alpha-(2-methyl-1-oxobutoxy)-mevinic acid lactone
6 alpha-Methylcompactin
6-alpha-Methylcompactin
6-Methylcompactin
6alpha-Methylcompactin
71949-96-7
74133-25-8
75330-75-5
81739-26-6
ACon0_000534
ACon1_000390
ADVICOR
AIDS-059059
AIDS059059
Altocor
Altoprev
Artein
BB_NC-1457
Belvas
BPBio1_000519
BRN 3631989
BSPBio_000471
BSPBio_001265
BSPBio_003346
Butanoic acid, 2-methyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (2S)-
Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-- oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))-
Butanoic acid, 2-methyl-, 1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester, (1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))-
Butanoic acid, 2-methyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester,(1S-(1alpha(R*),3alpha,7beta,8beta(2S*,4S*),8abeta))
C07074
C24H36O5
CHEBI:40303
Cholestra
Closterol
Colevix
CPD-5561
D00359
DB00227
DivK1c_001032
Hipolip
Hipovastin
HSDB 6534
IDI1_001032
KBio1_001032
KBio3_002848
L-154803
Lestatin
Lipdip
Lipivas
Lipofren
Liposcler
Lovalip
Lovalord
Lovastatin
Lovastatin (USP/INN)
Lovastatin [USAN:BAN:INN]
Lovastatina [Spanish]
Lovastatine [French]
Lovastatinum [Latin]
Lovasterol
Lovastin
Lozutin
LS-46359
M2147_SIGMA
MEGxm0_000398
Mevacor
Mevacor (TN)
Mevinacor
Mevinolin
Mevinolin from Aspergillus sp.
Mevlor
MK 803
MK-803
ML-530B
MLS000069585
MLS001055358
Monacolin K
Monakolin K
MSD 803
NCGC00023509-03
NCGC00023509-04
NCGC00023509-05
NCGC00023509-06
NCGC00023509-07
NCGC00023509-08
nchembio742-comp5
nchembio790-comp14
nchembio869-comp12
Nergadan
NINDS_001032
Paschol
Prestwick0_000516
Prestwick1_000516
Prestwick2_000516
Prestwick3_000516
Prestwick_819
Rextat
Rodatin
Rovacor
Sivlor
SMR000058779
SMR000673570
SPBio_002392
SPECTRUM1503977
Spectrum3_001873
Spectrum5_001294
Taucor
Tecnolip
Teroltrat
ZINC03812841
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate
ATC-Codes:
Side-Effects:
Side-EffectFrequency
flatulence0.03844681
constipation0.02666667
headache0.02510639
diarrhea0.022083335
myalgia0.021239998
abdominal pain0.02055555
nausea0.02025
dyspepsia0.012000002
asthenia0.011315788
rash0.010326085
blurred vision0.010114287
muscle cramps0.00782
dizziness0.0069230758
cirrhosis0.0010
hypercholesterolemia0.0010
vertigo0.0010
insomnia0.0010
pruritus0.0010
hepatoma0.0010
purpura0.0010
leg pain0.0010
tremor0.0010
rhabdomyolysis0.0010
myopathy0.0010
ophthalmoplegia0.0010
paresis0.0010
shoulder pain0.0010
pancreatitis0.0010
gynecomastia0.0010
memory loss0.0010
chest pain0.0010
coronary atherosclerosis0.0010
regurgitation0.0010
loss of libido0.0010
hepatic necrosis0.0010
nerve palsy0.0010
cataracts0.0010
chronic active hepatitis0.0010
dry mouth0.0010
hypersensitivity0.00057
arthralgia0.00057
dermatomyositis0.00055
photosensitivity0.00045
malaise0.00045
urticaria0.00045
stevens - johnson syndrome0.00045
thrombocytopenia0.00045
vasculitis0.00045
positive ana0.00045
chills0.00045
vomiting0.00045
polymyalgia rheumatica0.00045
erythema multiforme0.00045
toxic epidermal necrolysis0.00045
eosinophilia0.00045
dyspnea0.00045
arthritis0.00045
anxiety0.00045
anorexia0.00045
angioedema0.00045
hemolytic anemia0.00045
anaphylaxis0.00045
alopecia0.00045
fever0.00045
flushing0.00045
peripheral neuropathy0.00045
paresthesia0.00045
lupus0.00045
hepatitis0.00045
leukopenia0.00045
jaundice0.00045
back pain0
cancer0
urinary tract infection0
sinusitis0
pain0
influenza0
infection0
alkaline phosphatase increased0