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Name:Pioglitazone Hydrochloride
PubChem ID:4829
Pathway:Show KEGG pathways
InChI:InChI=1/C19H20N2O3S/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23)/f/h21H
SMILES:CCc1ccc(CCOc2ccc(cc2)CC2C(NC(=O)S2)=O)nc1

Properties:
Formula:C19H20N2O3SAtoms:25
Molecular Weight:356.439Rotatable Bonds:7
H-bond Acceptors:5H-bond Donors:0
logP:3.4884
Targets:
NameUniprot IDSourceReferencesInteraction
Amine oxidase [flavin-containing] BAOFB_HUMANBindingDB-shows
CREB3L2-PPARgammaQ86WD1_HUMANSuperTargetPMID 016210596shows
Cytochrome P450Q7Z448_HUMANSuperTargetPMID 015860655shows
Cytochrome P450Q86SK2_HUMANSuperTargetPMID 015860655shows
Cytochrome P450Q86SK3_HUMANSuperTargetPMID 015860655shows
Cytochrome P450 2C19CP2CJ_HUMANSuperCyp-shows
Cytochrome P450 2C8CP2C8_HUMANSuperTargetPMID 016299161shows
Cytochrome P450 2C9CP2C9_HUMANSuperCyp-shows
Cytochrome P450 2D6CP2D6_HUMANSuperCyp-shows
Cytochrome P450 3A4CP3A4_HUMANSuperCyp-shows
Cytochrome P450 CYP3A4Q9BZM0_HUMANSuperTargetPMID 015860655shows
Cytochrome P450 family 3 subfamily A polypeptide 4Q6GRK0_HUMANSuperTargetPMID 015860655shows
Peroxisome proliferative activated receptor gammaQ4W448_HUMANSuperTargetPMID 016210596shows
Peroxisome proliferative activated receptor gammaQ4W4C6_HUMANSuperTargetPMID 016210596shows
Peroxisome proliferative activated receptor gammaQ4W4C7_HUMANSuperTargetPMID 016210596shows
Peroxisome proliferative activated receptor gamma isoform 2 variantQ53EW1_HUMANSuperTargetPMID 016210596shows
Peroxisome proliferator activated-receptor gammaQ9UEF6_HUMANSuperTargetPMID 016210596shows
Peroxisome proliferator-activated receptor alphaPPARA_HUMANBindingDB-shows
Peroxisome proliferator-activated receptor gammaPPARG_HUMANBindingDB-shows
Peroxisome proliferator-activated receptor gamma 1Q6L9M1_HUMANSuperTargetPMID 016210596shows
Testicular acid phosphatasePPAT_HUMANSuperTarget-shows
Tyrosine-protein phosphatase non-receptor type 1PTN1_HUMANBindingDB-shows
Synonyms:
()-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione
()-5-[[4-[2-(5-ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione
(+-)-5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
(+/-)-5-[p-[2-(ethyl-2-pyridyl)ethoxy]benzyl]-2,4-thiazolidinedione
(+/-)-5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione
105355-27-9
111025-46-8
2,4-thiazolidinedione,
2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-
2,4-thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-, (+)-
2,4-Thiazolidinedione, 5-((4-(2-(5-ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-, (+-)-
2,4-thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]- (9CI)
2,4-thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, ()-
2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, (+/-)-
5-((4-(2-(5-Ethyl-2-pyridinyl)ethoxy)phenyl)methyl)-2,4-thiazolidinedione
5-(4-(2-(5-ethyl-2-pyridyl)ethoxy)benzyl)-2,4-thiazolidinedione
5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione
5-[[4-[2-(5-Ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
5-[[4-[2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
5-[[4-[2-[(5-ethyl-2-pyridyl)]ethoxy]phenyl]methyl]thiazolidine- 2,4-dione
5-{4-[2-(5-ethylpyridin-2-yl)ethoxy]benzyl}-1,3-thiazolidine-2,4-dione
Actos
Actos (TN)
AD 4833
AD-4833
BB_SC-4137
BSPBio_002723
C07675
C19H20N2O3S
CHEBI:8228
DB01132
Duetact
Glustin
HSDB 7322
KBio2_002103
KBio2_004671
KBio2_007239
KBio3_001943
KBioGR_001619
KBioSS_002103
LS-151327
NCGC00163128-01
NCGC00163128-02
nchembio790-comp10
Pioglitazona
Pioglitazona [INN-Spanish]
Pioglitazone
Pioglitazone Hydrochloride
Pioglitazone [BAN:INN]
Pioglitazone [INN:BAN]
Pioglitazonum
Pioglitazonum [INN-Latin]
SPBio_001897
Spectrum2_001679
Spectrum3_001002
Spectrum4_001130
Spectrum5_001480
Spectrum5_002067
Spectrum_001623
U 72107
U 72107A
U-72107
U-72107A
U-72107E
U72,107A
Zactos
ATC-Codes:
Side-Effects:
Side-EffectFrequency
peripheral edema0.0010
hepatic failure0.0010
edema0.0010
hepatitis0.0010
congestive heart failure0.0010
anemia0
pharyngitis0
sinusitis0
cerebrovascular accident0
tooth disorder0
upper respiratory tract infection0
weight gain0
myocardial ischemia0
liver function tests abnormal0
myalgia0
myocardial infarction0
ischemia0
angina pectoris0
transient ischemic attack0
chest pain0
diarrhea0
dyspnea0
headache0
heart disease0
heart failure0
hyperglycemia0
hypertension0
hypoglycemia0
ecg abnormal0