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Name:Chlorperphenazine
PubChem ID:4748
Pathway:Show KEGG pathways
InChI:InChI=1/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2
SMILES:c1ccc2c(c1)N(CCCN1CCN(CC1)CCO)c1cc(ccc1S2)Cl

Properties:
Formula:C21H26ClN3OSAtoms:27
Molecular Weight:403.969Rotatable Bonds:6
H-bond Acceptors:3H-bond Donors:0
logP:3.8835
Targets:
NameUniprot IDSourceReferencesInteraction
5-hydroxytryptamine receptor 75HT7R_HUMANBindingDB-shows
Alpha-1A adrenergic receptorADA1A_HUMANSuperTarget-shows
CalmodulinCALM_HUMANDrugBank-shows
Cytochrome P450Q6XP50_HUMANSuperTargetPMID 008689810shows
Cytochrome P450Q7Z448_HUMANSuperTargetPMID 011136295shows
Cytochrome P450Q86SK2_HUMANSuperTargetPMID 011136295shows
Cytochrome P450Q86SK3_HUMANSuperTargetPMID 011136295shows
Cytochrome P450 1A2CP1A2_HUMANSuperCypPMID 11136295shows
Cytochrome P450 2B6CP2B6_HUMANSuperCyp-shows
Cytochrome P450 2C18CP2CI_HUMANSuperCypPMID 11136295shows
Cytochrome P450 2C19CP2CJ_HUMANSuperCypPMID 11136295shows
Cytochrome P450 2C8CP2C8_HUMANSuperCyp-shows
Cytochrome P450 2C9CP2C9_HUMANSuperCypPMID 11136295shows
Cytochrome P450 2D6CP2D6_HUMANSuperTargetPMID 008689810shows
Cytochrome P450 3A4CP3A4_HUMANSuperTargetPMID 011136295shows
Cytochrome P450 CYP3A4Q9BZM0_HUMANSuperTargetPMID 011136295shows
Cytochrome P450 family 3 subfamily A polypeptide 4Q6GRK0_HUMANSuperTargetPMID 011136295shows
Cytochrome P450, family 2, subfamily D, polypeptide 6Q6NWU0_HUMANSuperTargetPMID 008689810shows
Cytochrome P450db1Q16804_HUMANSuperTargetPMID 008689810shows
D(1A) dopamine receptorDRD1_HUMANSuperTarget-shows
D(2) dopamine receptorDRD2_HUMANSuperTarget-shows
Sodium/potassium-transporting ATPase alpha-1 chainQ8HYW7_BOVINPROMISCUOUSPMID 134479shows
Sodium/potassium-transporting ATPase alpha-3 chainQ8HYW6_BOVINPROMISCUOUSPMID 134479shows
Sodium/potassium-transporting ATPase subunit alpha-1AT1A1_BOVINPROMISCUOUSPMID 134479shows
Sodium/potassium-transporting ATPase subunit alpha-2AT1A2_BOVINPROMISCUOUSPMID 134479shows
Synonyms:
.gamma.-[4-(.beta.-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazin
.gamma.-[4-(.beta.-Hydroxyethyl)piperazin-1-yl]propyl-2-chlorophenothiazine
1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina
1',1-(2-Idrossietil)-4,3-(2-cloro-10-fenotiazil)propilpiperazina [Italian]
1-(2-Hydroxyethyl)-4-(3-(2-chloro-10-phenothiazinyl)propyl)piperazine
1-(2-Hydroxyethyl)-4-[3-(2-chloro-10-phenothiazinyl)propyl]piperazine
1-Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)-
1-Piperazineethanol, 4-(3-(2-chlorophenothiazin-10-yl)propyl)-
1-Piperazineethanol, 4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-
1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-
1-Piperazineethanol, 4-[3-(2-chlorophenothiazin-10-yl)propyl]-, trihydrochloride
2-(4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]-1-piperazinyl)ethanol
2-Chloro-10-(3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl)phenothiazine
2-chloro-10-(3-(4-(2-hydroxyethyl)piperazin-1-yl)propyl)phenothiazine
2-Chloro-10-3-(1-(2-hydroxyethyl)-4-piperazinyl)propyl phenothiazine
2-Chloro-10-3-[1-(2-hydroxyethyl)-4-piperazinyl]propyl phenothiazine
2-Chloro-10-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propyl]phenothiazine
2-[4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl]ethanol
2-{4-[3-(2-chloro-10H-phenothiazin-10-yl)propyl]piperazin-1-yl}ethanol
2-{4-[3-(2-Chloro-phenothiazin-10-yl)-propyl]-piperazin-1-yl}-ethanol
2-{4-[3-(2-chlorophenothiazin-10-yl)propyl]piperazinyl}ethan-1-ol
4-(3-(2-Chlorophenothiazin-10-YL)propyl)-1-piperazineethanol
4-[3-(2-Chloro-10H-phenothiazin-10-yl)propyl]-1-piperazineethanol
4-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-piperazineethanol
58-39-9
AB00052390
AC-12196
AC1L1IVB
AI3-50151
AIDS-001621
AIDS001621
AKOS000664046
Apo-Perphenazine
BAS 00139131
BIDD:GT0150
BPBio1_000188
BRD-K10995081-001-05-5
BSPBio_000170
BSPBio_002376
C07427
C21H26ClN3OS
CAS-58-39-9
CCG-39060
CHEBI:8028
CHEMBL567
Chlorperphenazine
Chlorpiprazine
component of Etrafon
CPD000058180
D00503
DB00850
Decentan
DivK1c_000880
EINECS 200-381-5
Emesinal
Etaperazin
Etaperazine
Ethaperazine
Etrafon
ETRAFON 2-10
ETRAFON 2-25
ETRAFON-A
ETRAFON-FORTE
EU-0072164
EU-0100930
F-mon
Fentazin
gamma-(4-(beta-Hydroxyethyl)piperazin-1-yl)propyl-2-chlorophenothiazine
HMS1568I12
HMS1922M14
HMS2093M15
HMS2095I12
HMS2232D21
HMS3259C09
HMS3262J22
HMS502L22
HSDB 3379
I06-1508
IDI1_000880
KBio1_000880
KBio2_002090
KBio2_004658
KBio2_007226
KBio3_001596
KBioGR_001445
KBioSS_002090
L000919
Lopac-P-6402
Lopac0_000930
LS-112185
Mixture Name
MLS000069637
MLS001146929
NCGC00015826-01
NCGC00015826-02
NCGC00015826-03
NCGC00015826-04
NCGC00015826-05
NCGC00015826-06
NCGC00015826-07
NCGC00015826-08
NCGC00015826-09
NCGC00015826-10
NCGC00024092-03
NCGC00024092-04
NCGC00024092-05
NCGC00024092-06
nchembio873-comp26
NINDS_000880
NSC 150866
NSC150866
Oprea1_603835
P 6402
P6402_SIGMA
Perfenazina
Perfenazina [INN-Spanish]
Perfenazina [Italian]
Perfenazine
Perphenan
Perphenazin
Perphenazine
Perphenazine (JP15/USP/INN)
Perphenazine (JP16/USP/INN)
PERPHENAZINE AND AMITRIPTYLINE HCL
Perphenazine fendizoate
Perphenazine [BAN:INN:JAN]
Perphenazine [INN:BAN:JAN]
Perphenazine [Trilafon]
Perphenazinum
Perphenazinum [INN-Latin]
Piperazineethanol, 4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)-
Prestwick0_000125
Prestwick1_000125
Prestwick2_000125
Prestwick3_000125
Prestwick_536
PZC
SAM002264637
Sch 3940
SCH-3940
SMR000058180
SPBio_001603
SPBio_002109
SPECTRUM1503934
Spectrum2_001602
Spectrum3_000758
Spectrum4_000843
Spectrum5_001493
Spectrum_001610
SR-01000000137-4
ST079662
ST5299092
STK019818
STOCK1S-21551
Thilatazin
Tranquisan
Triavil
TRIAVIL 2-10
TRIAVIL 2-25
TRIAVIL 4-10
TRIAVIL 4-25
TRIAVIL 4-50
Trifaron
Trilafon
Trilafon (TN)
Trilifan
Triphenot
UNII-FTA7XXY4EZ
WLN: T C666 BN ISJ EG B3- AT6N DNTJ D2Q
ATC-Codes:
Side-Effects:
Side-EffectFrequency
insomnia0
tachycardia0
syncope0
swelling0
sweating0
spasm0
increased salivation0
shock0
seizures0
pigmentary retinopathy0
purpura0
pruritus0
polyuria0
paralytic ileus0
pancytopenia0
numbness0
nasal congestion0
lupus0
torticollis0
erythema0
tardive dyskinesia0
paralysis0
bradycardia0
photosensitivity0
blurred vision0
sore throat0
parkinson0
galactorrhea0
excitement0
muscle weakness0
peripheral edema0
photophobia0
agitation0
urinary retention0
dry mouth0
urticaria0
urinary incontinence0
leukopenia0
jaundice0
infection0
eczema0
dyskinesia0
somnolence0
dizziness0
diarrhea0
contact dermatitis0
exfoliative dermatitis0
dysphagia0
cough0
constipation0
confusion0
ataxia0
asthma0
anorexia0
angioedema0
hemolytic anemia0
amenorrhea0
edema0
eosinophilia0
siadh0
postural hypotension0
hypotension0
hypoglycemia0
breast enlargement0
hypertension0
hypersensitivity0
hyperphagia0
hyperglycemia0
hepatitis infectious0
cardiac arrest0
headache0
gynecomastia0
glycosuria0
glaucoma0
fever0
fecal impaction0
agranulocytosis0