Drug Details

Name:	CHEMBL1090143
PubChem ID:	46865419
Pathway:	Show KEGG pathways
InChI:	InChI=1S/C25H15F3N4OS/c26-25(27,28)18-5-1-4-17(11-18)23(33)32-19-6-2-3-16(12-19)22-20-13-21(15-7-9-29-10-8-15)34-24(20)31-14-30-22/h1-14H,(H,32,33)
SMILES:	O=C(c1cccc(c1)C(F)(F)F)Nc1cccc(c1)c1ncnc2c1cc(s2)c1ccncc1
Properties:	Formula: C25H15F3N4OS Atoms: 34 Molecular Weight: 476.473 Rotatable Bonds: 6 H-bond Acceptors: 6 H-bond Donors: 1 logP: 6.7644
Targets:	Name Uniprot ID Source References Interaction Cell division protein kinase 4 CDK4_HUMAN BindingDB - shows Inhibitor of nuclear factor kappa-B kinase subunit beta IKKB_HUMAN BindingDB - shows Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha isoform PK3CA_HUMAN BindingDB - shows Protein kinase C theta type KPCT_HUMAN BindingDB - shows Proto-oncogene tyrosine-protein kinase LCK LCK_HUMAN BindingDB - shows Proto-oncogene tyrosine-protein kinase Src SRC_HUMAN BindingDB - shows RAC-alpha serine/threonine-protein kinase AKT1_HUMAN BindingDB - shows Tyrosine-protein kinase BTK BTK_HUMAN BindingDB - shows Tyrosine-protein kinase ITK/TSK ITK_HUMAN BindingDB - shows enlarge table
Synonyms:	CHEBI:722163 CHEMBL1090143 enlarge table

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