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Name:Tolcapone
PubChem ID:4659569
Pathway:Show KEGG pathways
InChI:InChI=1/C14H11NO5/c1-8-2-4-9(5-3-8)13(17)10-6-11(15(19)20)14(18)12(16)7-10/h2-7,16,18H,1H3
SMILES:Cc1ccc(cc1)C(c1cc(c(c(c1)O)O)N(=O)=O)=O

Properties:
Formula:C14H11NO5Atoms:20
Molecular Weight:273.241Rotatable Bonds:3
H-bond Acceptors:5H-bond Donors:0
logP:3.0686
Targets:
Synonyms:
(3,4-Dihydroxy-5-nitrophenyl)(4-methylphenyl)methanone
(3,4-dihydroxy-5-nitrophenyl)-(4-methylphenyl)methanone
134308-13-7
3,4-Dihydroxy-4'-methyl-5-nitrobenzophenone
3,4-dihydroxy-5'-methyl-5-nitrobenzophenone
AC-791
AC1NFJIT
BIDD:GT0032
C066340
C07949
C14H11NO5
CCRIS 7904
CHEBI:367825
CHEMBL1324
CPD-7664
D00786
DB00323
FT-0082597
HMS2089K14
I14-13303
LS-91226
Methanone, (3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)-
Methanone,(3,4-dihydroxy-5-nitrophenyl)(4-methylphenyl)
NCGC00181767-01
NCGC00181767-02
Ro 40-7592
Ro-40-7592
Roche brand of tolcapone
Tasmar
Tasmar (TN)
Tolcapone
Tolcapone (JAN/USAN/INN)
Tolcapone [USAN:INN]
UNII-CIF6334OLY
ATC-Codes:
Side-Effects:
Side-EffectFrequency
urinary tract infection0
sinusitis0
increased salivation0
seborrhea0
rhinitis0
pulmonary embolism0
pulmonary edema0
psychosis0
pruritus0
cerebrovascular accident0
syncope0
urinary incontinence0
upper respiratory tract infection0
tremor0
tooth disorder0
tinnitus0
thrombocytopenia0
tenosynovitis0
tachycardia0
polyuria0
pneumonia0
pharyngitis0
tumor0
nausea0
myocardial infarction0
fungal infection0
muscle cramps0
meningitis0
leukemia0
laryngitis0
nervousness0
neuralgia0
pericardial effusion0
paresthesia0
weakness0
palpitations0
pain0
ovarian cancer0
otitis media0
nocturia0
lacrimation disorder0
allergic reaction0
bradycardia0
blurred vision0
hypoxia0
thinking abnormal0
myalgia0
malaise0
sinus congestion0
gastric stasis0
neuropathy0
manic0
breast neoplasm0
mental deficiency0
cerebral ischemia0
sleep disorder0
increased sweating0
urinary frequency0
prostate cancer0
abnormal gait0
eye pain0
myocardial ischemia0
migraine0
dry mouth0
weight loss0
vomiting0
viral infection0
viral hepatitis0
vertigo0
vaginitis0
uterine hemorrhage0
urinary retention0
choreoathetosis0
mouth ulceration0
cataract0
peripheral edema0
emotional lability0
apathy0
agitation0
chills0
encephalopathy0
urticaria0
somnolence0
coronary artery disease0
constipation0
confusion0
colitis0
cholelithiasis0
cholecystitis0
chest pain0
neck pain0
cough0
decreased libido0
dizziness0
diplopia0
diarrhea0
diabetes mellitus0
delusions0
delirium0
dehydration0
dysphagia0
cerebral hemorrhage0
cellulitis0
carcinoma0
aortic stenosis0
anxiety0
anorexia0
angina pectoris0
anemia0
amnesia0
alopecia0
abscess0
apnea0
arrhythmia0
bronchitis0
bacterial infections0
atrial fibrillation0
asthma0
asthenia0
arthritis0
arthralgia0
arteriosclerosis0
abdominal pain0
kidney calculus0
herpes simplex0
hernia0
hemorrhage0
hemiplegia0
hematuria0
heart failure0
cardiac arrest0
headache0
herpes zoster0
hiccup0
arthrosis0
irritability0
influenza0
infection0
impotence0
hypotension0
hypertension0
hypercholesterolemia0
hallucinations0
glaucoma0
gastrointestinal hemorrhage0
epistaxis0
edema0
eczema0
ear pain0
dysuria0
dyspnea0
dyspepsia0
dyskinesia0
erythema multiforme0
esophagitis0
gastroenteritis0
furunculosis0
flatulence0
flank pain0
fever0
fatigue0
rash0
euphoria0
duodenal ulcer0