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Drug Details

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Name:Kinome_2481
PubChem ID:46224684
Pathway:Show KEGG pathways
InChI:InChI=1S/C23H19N7S/c24-5-6-30-12-17(22-18(30)11-26-23(25)28-22)14-7-15-10-27-29-21(15)16(8-14)20-9-13-3-1-2-4-19(13)31-20/h1-4,7-12H,5-6,24H2,(H,27,29)(H2,25,26,28)
SMILES:NCCn1cc(c2c1cnc(n2)N)c1cc2cn[nH]c2c(c1)c1cc2c(s1)cccc2

Properties:
Formula:C23H19N7SAtoms:31
Molecular Weight:425.509Rotatable Bonds:4
H-bond Acceptors:7H-bond Donors:3
logP:5.6787
Targets:
NameUniprot IDSourceReferencesInteraction
3-phosphoinositide-dependent protein kinase 1PDPK1_HUMANBindingDB-shows
Basic fibroblast growth factor receptor 1FGFR1_HUMANBindingDB-shows
Cell division protein kinase 2CDK2_HUMANBindingDB-shows
Ephrin type-A receptor 2EPHA2_HUMANBindingDB-shows
Epidermal growth factor receptorEGFR_HUMANBindingDB-shows
Fibroblast growth factor receptor 3FGFR3_HUMANBindingDB-shows
FL cytokine receptorFLT3_HUMANBindingDB-shows
Glycogen synthase kinase-3 alphaGSK3A_HUMANBindingDB-shows
Glycogen synthase kinase-3 betaGSK3B_HUMANBindingDB-shows
Hepatocyte growth factor receptorMET_HUMANBindingDB-shows
High affinity immunoglobulin gamma Fc receptor IFCGR1_HUMANBindingDB-shows
High affinity nerve growth factor receptorNTRK1_HUMANBindingDB-shows
Inhibitor of nuclear factor kappa-B kinase subunit alphaIKKA_HUMANBindingDB-shows
Macrophage colony-stimulating factor 1 receptorCSF1R_HUMANBindingDB-shows
MAP kinase-activated protein kinase 2MAPK2_HUMANBindingDB-shows
Mast/stem cell growth factor receptorKIT_HUMANBindingDB-shows
Mitogen-activated protein kinase 1MK01_HUMANBindingDB-shows
Mitogen-activated protein kinase 12MK12_HUMANBindingDB-shows
Proto-oncogene serine/threonine-protein kinase Pim-1PIM1_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase ABL1ABL1_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase FynFYN_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase LCKLCK_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase SrcSRC_HUMANBindingDB-shows
RAC-alpha serine/threonine-protein kinaseAKT1_HUMANBindingDB-shows
Receptor tyrosine-protein kinase erbB-2ERBB2_HUMANBindingDB-shows
Rho-associated protein kinase 1ROCK1_HUMANBindingDB-shows
Ribosomal protein S6 kinase beta-1KS6B1_HUMANBindingDB-shows
Serine/threonine-protein kinase 6STK6_HUMANBindingDB-shows
Serine/threonine-protein kinase PLK1PLK1_HUMANBindingDB-shows
Tyrosine-protein kinase ITK/TSKITK_HUMANBindingDB-shows
Tyrosine-protein kinase JAK2JAK2_HUMANBindingDB-shows
Tyrosine-protein kinase JAK3JAK3_HUMANBindingDB-shows
Tyrosine-protein kinase SYKKSYK_HUMANBindingDB-shows
Vascular endothelial growth factor receptor 1VGFR1_HUMANBindingDB-shows
Vascular endothelial growth factor receptor 2VGFR2_HUMANBindingDB-shows
Vascular endothelial growth factor receptor 3VGFR3_HUMANBindingDB-shows
Synonyms:
CHEBI:690207
CHEMBL590109
Kinome_2481