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Drug Details

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Name:NAD
PubChem ID:449328
Pathway:Show KEGG pathways
InChI:InChI=1/C21H25N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-15,20,29-31H,5-6H2,(H6-,22,23,24,25,32,33,34,35,36,37)/p+1/t10-,11-,13-,14-,15-,20-/m1/s1/fC21H26N7O14P2/h32,34,36H,22-23H2/q+1
SMILES:c1cc(c[n+](c1)[C@H]1([C@H]([C@H]([C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2[C@H](C(=C(n3cnc4c(N)ncnc34)O2)O)O)O1)O)O))C(N)=O

Properties:
Formula:C21H26N7O14P2Atoms:50
Molecular Weight:662.417Rotatable Bonds:11
H-bond Acceptors:19H-bond Donors:0
logP:-0.9098
Targets:
NameUniprot IDSourceReferencesInteraction
2,3-diketo-L-gulonate reductaseDLGD_ECOLIDrugBank-shows
2,5-diketo-D-gluconic acid reductase ADKGA_CORSCDrugBank-shows
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenaseHSD_STREXDrugBank-shows
3-alpha-(or 20-beta)-hydroxysteroid dehydrogenaseHSD_MYCTUDrugBank-shows
3-dehydroquinate synthaseAROB_STAARDrugBank-shows
3-hydroxy-3-methylglutaryl-coenzyme A reductaseMVAA_PSEMVDrugBank-shows
3-hydroxyacyl-CoA dehydrogenase type-2HCD2_RATDrugBank-shows
3-hydroxyacyl-CoA dehydrogenase type-2HCD2_HUMANDrugBank-shows
3-isopropylmalate dehydrogenaseLEU3_THET8DrugBank-shows
3-oxoacyl-(Acyl carrier protein) reductaseQ9X0Q1_THEMADrugBank-shows
3alpha-hydroxysteroid dehydrogenase/carbonyl reductaseQ9ZFY9_COMTEDrugBank-shows
6-phospho-beta-glucosidase bglTBGLT_THEMADrugBank-shows
7-alpha-hydroxysteroid dehydrogenaseHDHA_ECOLIDrugBank-shows
Acetoin(diacetyl) reductaseBUDC_KLEPNDrugBank-shows
AdenosylhomocysteinaseSAHH_RATDrugBank-shows
AdenosylhomocysteinaseSAHH_HUMANDrugBank-shows
AdenosylhomocysteinaseSAHH_PLAF7DrugBank-shows
ADP-ribosyltransferaseQ9ADS9_STAAUDrugBank-shows
Alanine dehydrogenaseO52942_PHOLPDrugBank-shows
Alcohol dehydrogenaseADH_DROMEDrugBank-shows
Alcohol dehydrogenaseQ9HTD9_PSEAEDrugBank-shows
Alcohol dehydrogenaseADH_DROLEDrugBank-shows
Alcohol dehydrogenase 1ADH1_GADCADrugBank-shows
Alcohol dehydrogenase 1AADH1A_HUMANDrugBank-shows
Alcohol dehydrogenase 1BADH1B_HUMANDrugBank-shows
Alcohol dehydrogenase 1CADH1G_HUMANDrugBank-shows
Alcohol dehydrogenase 4ADH4_MOUSEDrugBank-shows
Alcohol dehydrogenase class 4 mu/sigma chainADH7_HUMANDrugBank-shows
Alcohol dehydrogenase class-3ADHX_HUMANDrugBank-shows
Alcohol dehydrogenase E chainADH1E_HORSEDrugBank-shows
Alcohol dehydrogenase S chainADH1S_HORSEDrugBank-shows
Aldehyde dehydrogenase, cytosolic 1ALDH1_ELEEDDrugBank-shows
Aldehyde dehydrogenase, dimeric NADP-preferringAL3A1_RATDrugBank-shows
Aldehyde dehydrogenase, mitochondrialALDH2_BOVINDrugBank-shows
Aldehyde dehydrogenase, mitochondrialALDH2_HUMANDrugBank-shows
Alpha-glucosidaseAGLA_THEMADrugBank-shows
Alpha-glucosidase, putativeQ9WZL1_THEMADrugBank-shows
Benzyl alcohol dehydrogenaseQ59096_ACICADrugBank-shows
Betaine aldehyde dehydrogenaseBADH_GADCADrugBank-shows
Bifunctional protein GAL10GAL10_YEASTDrugBank-shows
Biliverdin reductase ABIEA_RATDrugBank-shows
C-terminal-binding protein 1CTBP1_HUMANDrugBank-shows
C-terminal-binding protein 1CTBP1_RATDrugBank-shows
CDP-D-glucose-4,6-dehydrataseQ57329_YERPSDrugBank-shows
CDP-paratose 2-epimeraseRFBE_SALTIDrugBank-shows
Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenaseBPHB_BURXLDrugBank-shows
Citrate synthaseCISY_ECOLIDrugBank-shows
D-2-hydroxyisocaproate dehydrogenaseDHD2_LACPADrugBank-shows
D-3-phosphoglycerate dehydrogenaseSERA_ECOLIDrugBank-shows
D-lactate dehydrogenaseLDHD_LACDADrugBank-shows
D-lactate dehydrogenaseLDHD_LACHEDrugBank-shows
DehydrogenaseQ746L8_THET2DrugBank-shows
Deoxyhypusine synthaseDHYS_HUMANDrugBank-shows
Dihydrodipicolinate reductaseDAPB_THEMADrugBank-shows
Dihydrodipicolinate reductaseDAPB_MYCTUDrugBank-shows
Dihydrodipicolinate reductaseDAPB_ECOLIDrugBank-shows
Dihydrolipoyl dehydrogenaseDLDH1_PSEPUDrugBank-shows
Dihydrolipoyl dehydrogenase, mitochondrialDLDH_YEASTDrugBank-shows
Dihydropteridine reductaseDHPR_RATDrugBank-shows
Dihydropteridine reductaseDHPR_HUMANDrugBank-shows
Diphtheria toxinDTX_COROMDrugBank-shows
DNA ligaseDNLJ_ENTFADrugBank-shows
dTDP-4-dehydrorhamnose reductaseRFBD_SALTYDrugBank-shows
dTDP-glucose 4,6-dehydrataseRMLB_STRMUDrugBank-shows
dTDP-glucose 4,6-dehydrataseRFBB_SALTYDrugBank-shows
dTDP-glucose 4,6-dehydrataseQ9ZGH3_9ACTODrugBank-shows
Enoyl-[acyl-carrier-protein] reductase [NADH]FABI_HELPYDrugBank-shows
Enoyl-[acyl-carrier-protein] reductase [NADH]FABI_ECOLIDrugBank-shows
Enoyl-[acyl-carrier-protein] reductase [NADH]INHA_MYCTUDrugBank-shows
Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplasticFABI_BRANADrugBank-shows
Estradiol 17-beta-dehydrogenase 1DHB1_HUMANDrugBank-shows
Ferredoxin reductaseQ52437_PSES1DrugBank-shows
Formate dehydrogenaseFDH_PSESRDrugBank-shows
Gamma-aminobutyraldehyde dehydrogenaseABDH_ECOLIDrugBank-shows
GDP-mannose 6-dehydrogenaseALGD_PSEAEDrugBank-shows
Glucose 1-dehydrogenaseDHG_BACMEDrugBank-shows
Glucose--fructose oxidoreductaseGFO_ZYMMODrugBank-shows
Glucose-6-phosphate 1-dehydrogenaseG6PD_LEUMEDrugBank-shows
Glutamate dehydrogenaseQ9Y8I4_PYRISDrugBank-shows
Glutamate dehydrogenase 1, mitochondrialDHE3_BOVINDrugBank-shows
Glutathione reductaseGSHR_ECOLIDrugBank-shows
Glutathione reductase, mitochondrialGSHR_HUMANDrugBank-shows
Glutathione-independent formaldehyde dehydrogenaseFADH_PSEPUDrugBank-shows
Glyceraldehyde 3-phosphate dehydrogenaseP84125_THETHDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenaseG3P_BACSTDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenaseG3P_HOMAMDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenaseG3P_THEAQDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenaseG3P_HUMANDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenaseG3P_PANVRDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenaseG3P_THEMADrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenase (NADP+)O57693_THETEDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenase AG3P1_ECOLIDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenase A, chloroplasticG3PA_SPIOLDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenase, glycosomalG3PG_TRYBBDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenase, glycosomalG3PG_TRYCRDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenase, glycosomalG3PG_LEIMEDrugBank-shows
Glycerol dehydrogenaseGLDA_BACSTDrugBank-shows
Glycerol-3-phosphate dehydrogenase [NAD+], glycosomalGPDA_LEIMEDrugBank-shows
Histidinol dehydrogenaseHISX_ECOLIDrugBank-shows
Homoserine dehydrogenaseDHOM_YEASTDrugBank-shows
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialHCDH_HUMANDrugBank-shows
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialHCDH_PIGDrugBank-shows
Inorganic polyphosphate/ATP-NAD kinasePPNK_MYCTUDrugBank-shows
Inosine-5'-monophosphate dehydrogenaseIMDH_TRIFODrugBank-shows
Inosine-5'-monophosphate dehydrogenase 2IMDH2_HUMANDrugBank-shows
Inositol-3-phosphate synthaseINO1_YEASTDrugBank-shows
Iota toxin component IaQ46220_CLOPEDrugBank-shows
Isocitrate dehydrogenase [NADP]IDH_ECOLIDrugBank-shows
L-2-hydroxyisocaproate dehydrogenaseDHL2_LACCODrugBank-shows
L-aspartate dehydrogenaseASPD_THEMADrugBank-shows
L-lactate dehydrogenaseLDH_LACPEDrugBank-shows
L-lactate dehydrogenaseLDH_BACSTDrugBank-shows
L-lactate dehydrogenaseLDH_PLAFDDrugBank-shows
L-lactate dehydrogenaseLDH_THEMADrugBank-shows
L-lactate dehydrogenaseLDH_TOXGODrugBank-shows
L-lactate dehydrogenase 2LDH2_BIFLODrugBank-shows
L-lactate dehydrogenase A chainLDHA_SQUACDrugBank-shows
L-lactate dehydrogenase B chainLDHB_HUMANDrugBank-shows
L-sulfolactate dehydrogenaseCOMC_METJADrugBank-shows
Lactate dehydrogenaseP90613_TOXGODrugBank-shows
Levodione reductaseLVR_LEIAQDrugBank-shows
Malate dehydrogenaseMDH_THETHDrugBank-shows
Malate dehydrogenaseMDH_HALMADrugBank-shows
Malate dehydrogenaseMDH_CHLVIDrugBank-shows
Malate dehydrogenaseMDH_CHLAADrugBank-shows
Malate dehydrogenaseMDH_ECOLIDrugBank-shows
Malate dehydrogenaseMDH_AQUARDrugBank-shows
Malate dehydrogenaseMDH_ARCFUDrugBank-shows
Malate dehydrogenaseMDH_CHLTEDrugBank-shows
Malate dehydrogenase, cytoplasmicMDHC_PIGDrugBank-shows
Maltose-6'-phosphate glucosidaseGLVA_BACSUDrugBank-shows
Mannitol dehydrogenaseO08355_PSEFLDrugBank-shows
Methylenetetrahydrofolate dehydrogenase [NAD+]MTD1_YEASTDrugBank-shows
Mono-ADP-ribosyltransferase C3ARC3_CBDPDrugBank-shows
Myo-inositol-1-phosphate synthase (Ino1)O28480_ARCFUDrugBank-shows
Myo-inositol-1-phosphate synthase-related proteinQ9X1D6_THEMADrugBank-shows
NAD(P) transhydrogenase subunit alpha part 1PNTAA_RHORUDrugBank-shows
NAD(P)H-dependent D-xylose reductaseXYL1_CANTEDrugBank-shows
NAD-dependent alcohol dehydrogenaseADH_SULSODrugBank-shows
NAD-dependent deacetylase 1NPD1_ARCFUDrugBank-shows
NAD-dependent deacetylase 2NPD2_ARCFUDrugBank-shows
NAD-dependent malic enzyme, mitochondrialMAOM_HUMANDrugBank-shows
NAD-dependent malic enzyme, mitochondrialMAOM_ASCSUDrugBank-shows
NADH peroxidaseNAPE_ENTFADrugBank-shows
NADH-cytochrome b5 reductase 3NB5R3_RATDrugBank-shows
NADPH-flavin oxidoreductaseFRP_VIBHADrugBank-shows
NH(3)-dependent NAD(+) synthetaseNADE_ECOLIDrugBank-shows
NH(3)-dependent NAD(+) synthetaseNADE_BACSUDrugBank-shows
Nicotinamide mononucleotide adenylyltransferase 1NMNA1_HUMANDrugBank-shows
Nicotinamide mononucleotide adenylyltransferase 3NMNA3_HUMANDrugBank-shows
Nicotinamide-nucleotide adenylyltransferaseNADM_METTHDrugBank-shows
Nicotinate-nucleotide adenylyltransferaseNADD_SHIFLDrugBank-shows
Nitric oxide synthase oxygenaseNOSO_STAAWDrugBank-shows
Nitrogen metabolite repression regulator NmrAO59919_EMENIDrugBank-shows
Ornithine cyclodeaminaseQ88H32_PSEPKDrugBank-shows
Ornithine cyclodeaminase (ArcB)O28608_ARCFUDrugBank-shows
Pentafunctional AROM polypeptideARO1_EMENIDrugBank-shows
Peroxisomal multifunctional enzyme type 2DHB4_HUMANDrugBank-shows
Phenol 2-hydroxylase component BQ9LAG2_BACTRDrugBank-shows
Probable inorganic polyphosphate/ATP-NAD kinasePPNK_ARCFUDrugBank-shows
Protein VF13D12L.1, confirmed by transcript evidenceQ18664_CAEELDrugBank-shows
Putative malate dehydrogenaseQ7CRW4_AGRT5DrugBank-shows
Putative quinone oxidoreductase yhfPYHFP_BACSUDrugBank-shows
Quinate/shikimate dehydrogenaseYDIB_ECOLIDrugBank-shows
Redox-sensing transcriptional repressor rexREX_THEAQDrugBank-shows
Retinal dehydrogenase 1AL1A1_SHEEPDrugBank-shows
Retinal dehydrogenase 2AL1A2_RATDrugBank-shows
Siroheme biosynthesis protein MET8MET8_YEASTDrugBank-shows
Siroheme synthaseCYSG_SALTYDrugBank-shows
Sorbitol dehydrogenaseDHSO_HUMANDrugBank-shows
T-cell ecto-ADP-ribosyltransferase 2NAR2B_RATDrugBank-shows
Transcriptional regulator nadRNADR_HAEINDrugBank-shows
Trk system potassium uptake protein trkA homologTRKA_METJADrugBank-shows
UDP-galactose 4-epimeraseQ8T8E9_9TRYPDrugBank-shows
UDP-glucose 4-epimeraseGALE_HUMANDrugBank-shows
UDP-glucose 4-epimeraseGALE_ECOLIDrugBank-shows
UDP-glucose 6-dehydrogenaseUDG_STRPYDrugBank-shows
UDP-sulfoquinovose synthase, chloroplasticSQD1_ARATHDrugBank-shows
Uncharacterized protein Rv0046c/MT0052Y046_MYCTUDrugBank-shows
Urocanate hydrataseHUTU_PSEPKDrugBank-shows
Vip2AcQ844J9_BACTUDrugBank-shows
WbpPQ8KN66_PSEAEDrugBank-shows
Synonyms:
AC1L9MZV
CID449328
NAD
[[(2R,3R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-2,3-dihydrofuran-2-yl]methox