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Drug Details

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Name:Dithiothreitol
PubChem ID:446094
Pathway:Show KEGG pathways
InChI:InChI=1/C4H10O2S2/c5-3(1-7)4(6)2-8/h3-8H,1-2H2/t3-,4-/m1/s1
SMILES:C([C@H]([C@H](CS)O)O)S

Properties:
Formula:C4H10O2S2Atoms:10
Molecular Weight:154.251Rotatable Bonds:3
H-bond Acceptors:2H-bond Donors:0
logP:-0.4322
Targets:
NameUniprot IDSourceReferencesInteraction
3-carboxy-cis,cis-muconate cycloisomerasePCAB_PSEPUDrugBank-shows
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMDH_HUMANDrugBank-shows
50S ribosomal protein L27RL27_THET8DrugBank-shows
6,7-dimethyl-8-ribityllumazine synthaseRISB_MYCTUDrugBank-shows
Acetolactate synthase catalytic subunit, mitochondrialILVB_YEASTDrugBank-shows
Alcohol dehydrogenaseADH_DROLEDrugBank-shows
Aldehyde dehydrogenase, cytosolic 1ALDH1_ELEEDDrugBank-shows
AmylosucraseAMYS_NEIPODrugBank-shows
Axin-1AXN1_HUMANDrugBank-shows
Beta-alanine synthaseQ96W94_SACKLDrugBank-shows
Beta-amylaseAMYB_IPOBADrugBank-shows
C protein alpha-antigenBCA_STRA1DrugBank-shows
Calcium/calmodulin-dependent protein kinase type II alpha chainKCC2A_RATDrugBank-shows
Chaperone protein torDTORD_SHEMADrugBank-shows
Galectin-1LEG1_BUFARDrugBank-shows
Histidinol dehydrogenaseHISX_ECOLIDrugBank-shows
Holo-[acyl-carrier-protein] synthaseACPS_BACSUDrugBank-shows
Listeriolysin regulatory proteinPRFA_LISMODrugBank-shows
Maleylacetoacetate isomeraseMAAI_HUMANDrugBank-shows
Molybdenum cofactor biosynthesis protein AMOAA_STAAWDrugBank-shows
Organic hydroperoxide resistance proteinQ9HZZ3_PSEAEDrugBank-shows
Peptide methionine sulfoxide reductaseMSRA_BOVINDrugBank-shows
Peptidyl-prolyl cis-trans isomerase 5CYP5_CAEELDrugBank-shows
Protease synthase and sporulation negative regulatory protein PAI 1PAIA_BACSUDrugBank-shows
Receptor-type adenylate cyclase GRESAG 4.1CY41_TRYBBDrugBank-shows
Shikimate dehydrogenaseAROE_ECOLIDrugBank-shows
Thymidylate synthaseTYSY_ECOLIDrugBank-shows
Transient receptor potential cation channel subfamily M member 7TRPM7_MOUSEDrugBank-shows
Triosephosphate isomerase, glycosomalTPIS_TRYBBDrugBank-shows
Unsaturated glucuronyl hydrolaseUGL_BACGLDrugBank-shows
Synonyms:
()-1,4-dimercapto-2,3-butanediol
()-dithiothreitol
()-threo-1,4-Dimercapto-2,3-butanediol solution
(+/-)-1,4-Dimercapto-2,3-butanediol
(+/-)-Dithiothreitol
(+/-)-threo-1,4-Dimercapto-2,3-butanediol solution
(2S,3S)-1,4-bis(sulfanyl)butane-2,3-diol
(2S,3S)-1,4-DIMERCAPTOBUTANE-2,3-DIOL
(2S,3S)-1,4-disulfanylbutane-2,3-diol
1,4-Dithio-DL-threitol
1,4-Dithiothreitol
2,3-butanediol, 1,4-dimercapto-
2,3-Butanediol, 1,4-dimercapto-, (2R,3R)-rel- (9CI)
2,3-Butanediol, 1,4-dimercapto-, (R*,R*)-
2,3-DIHYDROXY-1,4-DITHIOBUTANE
27565-41-9
3483-12-3
43815_FLUKA
43815_SIGMA
43816_FLUKA
43816_SIGMA
43817_FLUKA
43817_SIGMA
646563_SIGMA
AC1L9J3L
CHEBI:42170
CHEMBL1232392
Cleland's reagent
D-1,4-dithiothreitol
D-DTT
D-threo-1,4-dimercapto-2,3-butanediol
D0632_SIAL
D5545_SIAL
D9163_SIGMA
D9779_SIGMA
DB01692
DB02184
DB04447
Dithiothreitol
DL-1,4-Dimercapto-2,3-dihydroxybutane
DL-1,4-Dithiothreitol
DL-Dithiothreitol
DL-Dithiothreitol solution
DTT
DTT (threitol derivative)
DTV
FT-0082717
LS-153740
LT03328513
nchembio.121-comp22
rac-Dithiothreitol
Reagents, Cleland's
Sputolysin
Threitol, 1,4-dithio- (7CI,8CI)
threo-1,4-Dimercapto-2,3-butanediol
threo-2,3-Dihydroxy-1,4-butanedithiol
WR 34678
ZINC03852211