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Drug Details

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Name:NITD609
PubChem ID:44469321
Pathway:Show KEGG pathways
InChI:InChI=1S/C19H14Cl2FN3O/c1-8-4-11-10-6-14(22)13(21)7-16(10)23-17(11)19(25-8)12-5-9(20)2-3-15(12)24-18(19)26/h2-3,5-8,23,25H,4H2,1H3,(H,24,26)/t8-,19+/m0/s1
SMILES:C[C@H]1Cc2c3cc(F)c(cc3[nH]c2[C@@]2(N1)C(=O)Nc1c2cc(Cl)cc1)Cl

Properties:
Formula:C19H14Cl2FN3OAtoms:26
Molecular Weight:390.238Rotatable Bonds:0
H-bond Acceptors:3H-bond Donors:3
logP:4.8105
Targets:
NameUniprot IDSourceReferencesInteraction
5-hydroxytryptamine receptor 1A5HT1A_HUMANBindingDB-shows
5-hydroxytryptamine receptor 2A5HT2A_HUMANBindingDB-shows
5-hydroxytryptamine receptor 2C5HT2C_HUMANBindingDB-shows
5-hydroxytryptamine receptor 3A5HT3A_HUMANBindingDB-shows
Adenosine A3 receptorAA3R_HUMANBindingDB-shows
Adenosine receptor A2aAA2AR_HUMANBindingDB-shows
Alpha-1A adrenergic receptorADA1A_HUMANBindingDB-shows
Alpha-2A adrenergic receptorADA2A_HUMANBindingDB-shows
Alpha-2B adrenergic receptorADA2B_HUMANBindingDB-shows
Alpha-2C adrenergic receptorADA2C_HUMANBindingDB-shows
Amine oxidase [flavin-containing] AAOFA_HUMANBindingDB-shows
Androgen receptorANDR_HUMANBindingDB-shows
B2 bradykinin receptorBKRB2_HUMANBindingDB-shows
Beta-1 adrenergic receptorADRB1_HUMANBindingDB-shows
Beta-3 adrenergic receptorADRB3_HUMANBindingDB-shows
cAMP-specific 3',5'-cyclic phosphodiesterase 4DPDE4D_HUMANBindingDB-shows
Cholecystokinin receptor type ACCKAR_HUMANBindingDB-shows
Cytochrome P450 2C9CP2C9_HUMANBindingDB-shows
D(1A) dopamine receptorDRD1_HUMANBindingDB-shows
D(2) dopamine receptorDRD2_HUMANBindingDB-shows
D(3) dopamine receptorDRD3_HUMANBindingDB-shows
Delta-type opioid receptorOPRD_HUMANBindingDB-shows
Endothelin B receptorEDNRB_HUMANBindingDB-shows
Endothelin-1 receptorEDNRA_HUMANBindingDB-shows
Estrogen receptorESR1_HUMANBindingDB-shows
Estrogen receptor betaESR2_HUMANBindingDB-shows
Gastrin/cholecystokinin type B receptorGASR_HUMANBindingDB-shows
Glucagon receptorGLR_HUMANBindingDB-shows
Glucocorticoid receptorGCR_HUMANBindingDB-shows
Histamine H1 receptorHRH1_HUMANBindingDB-shows
Histamine H2 receptorHRH2_HUMANBindingDB-shows
Histamine H3 receptorHRH3_HUMANBindingDB-shows
Kappa-type opioid receptorOPRK_HUMANBindingDB-shows
Mu-type opioid receptorOPRM_HUMANBindingDB-shows
Muscarinic acetylcholine receptor M1ACM1_HUMANBindingDB-shows
Muscarinic acetylcholine receptor M2ACM2_HUMANBindingDB-shows
Muscarinic acetylcholine receptor M3ACM3_HUMANBindingDB-shows
Potassium voltage-gated channel subfamily H member 2KCNH2_HUMANBindingDB-shows
Prostaglandin G/H synthase 1PGH1_HUMANBindingDB-shows
Prostaglandin G/H synthase 2PGH2_HUMANBindingDB-shows
Sodium-dependent dopamine transporterSC6A3_HUMANBindingDB-shows
Sodium-dependent noradrenaline transporterSC6A2_HUMANBindingDB-shows
Sodium-dependent serotonin transporterSC6A4_HUMANBindingDB-shows
Substance-P receptorNK1R_HUMANBindingDB-shows
Thromboxane A2 receptorTA2R_HUMANBindingDB-shows
Type-1 angiotensin II receptorAGTR1_HUMANBindingDB-shows
Vasopressin V1a receptorV1AR_HUMANBindingDB-shows
Vasopressin V2 receptorV2R_HUMANBindingDB-shows
Synonyms:
CHEBI:730274
CHEMBL1082723
NITD609