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Name:Kinome_2918
PubChem ID:44444843
Pathway:Show KEGG pathways
InChI:InChI=1S/C20H18ClN7O3S/c21-13-5-15-17(6-14(13)24-9-12-8-23-11-32-12)30-3-1-2-4-31-19-16(7-22)25-10-18(27-19)28-20(29)26-15/h5-6,8,10-11,24H,1-4,9H2,(H2,26,27,28,29)
SMILES:N#Cc1ncc2nc1OCCCCOc1c(NC(=O)N2)cc(Cl)c(c1)NCc1cncs1

Properties:
Formula:C20H18ClN7O3SAtoms:32
Molecular Weight:471.92Rotatable Bonds:3
H-bond Acceptors:11H-bond Donors:3
logP:4.61468
Targets:
NameUniprot IDSourceReferencesInteraction
5'-AMP-activated protein kinase subunit beta-1AAKB1_HUMANBindingDB-shows
Basic fibroblast growth factor receptor 1FGFR1_HUMANBindingDB-shows
Casein kinase I isoform gamma-2KC1G2_HUMANBindingDB-shows
Casein kinase II subunit alphaCSK21_HUMANBindingDB-shows
Cell division protein kinase 2CDK2_HUMANBindingDB-shows
Cell division protein kinase 5CDK5_HUMANBindingDB-shows
Cell division protein kinase 6CDK6_HUMANBindingDB-shows
Cell division protein kinase 7CDK7_HUMANBindingDB-shows
Cell division protein kinase 9CDK9_HUMANBindingDB-shows
Ephrin type-A receptor 2EPHA2_HUMANBindingDB-shows
Epidermal growth factor receptorEGFR_HUMANBindingDB-shows
Fibroblast growth factor receptor 3FGFR3_HUMANBindingDB-shows
FL cytokine receptorFLT3_HUMANBindingDB-shows
Glycogen synthase kinase-3 alphaGSK3A_HUMANBindingDB-shows
Glycogen synthase kinase-3 betaGSK3B_HUMANBindingDB-shows
High affinity nerve growth factor receptorNTRK1_HUMANBindingDB-shows
Inhibitor of nuclear factor kappa-B kinase subunit alphaIKKA_HUMANBindingDB-shows
Inhibitor of nuclear factor kappa-B kinase subunit betaIKKB_HUMANBindingDB-shows
Insulin receptorINSR_HUMANBindingDB-shows
Insulin-like growth factor 1 receptorIGF1R_HUMANBindingDB-shows
MAP kinase-activated protein kinase 2MAPK2_HUMANBindingDB-shows
Mast/stem cell growth factor receptorKIT_HUMANBindingDB-shows
Mitogen-activated protein kinase 1MK01_HUMANBindingDB-shows
Mitogen-activated protein kinase 12MK12_HUMANBindingDB-shows
Proto-oncogene serine/threonine-protein kinase Pim-1PIM1_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase ABL1ABL1_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase FynFYN_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase LCKLCK_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase SrcSRC_HUMANBindingDB-shows
RAC-alpha serine/threonine-protein kinaseAKT1_HUMANBindingDB-shows
Receptor tyrosine-protein kinase erbB-2ERBB2_HUMANBindingDB-shows
Rho-associated protein kinase 1ROCK1_HUMANBindingDB-shows
Ribosomal protein S6 kinase alpha-5KS6A5_HUMANBindingDB-shows
Ribosomal protein S6 kinase beta-1KS6B1_HUMANBindingDB-shows
Serine/threonine-protein kinase PLK1PLK1_HUMANBindingDB-shows
Tyrosine-protein kinase ITK/TSKITK_HUMANBindingDB-shows
Tyrosine-protein kinase JAK2JAK2_HUMANBindingDB-shows
Tyrosine-protein kinase JAK3JAK3_HUMANBindingDB-shows
Vascular endothelial growth factor receptor 1VGFR1_HUMANBindingDB-shows
Vascular endothelial growth factor receptor 2VGFR2_HUMANBindingDB-shows
Vascular endothelial growth factor receptor 3VGFR3_HUMANBindingDB-shows
Synonyms:
CHEBI:518190
CHEMBL248757
Kinome_2918