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Name:dihydrodiphosphopyridine nucleotide
PubChem ID:439153
Pathway:Show KEGG pathways
InChI:InChI=1/C21H29N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1/f/h34,36H,22-23H2
SMILES:C=1CC(=CN(C1)[C@H]1([C@H]([C@H]([C@@H](COP(O)(=O)OP(O)(=O)OC[C@H]2[C@H]([C@H]([C@@H](n3cnc4c(N)ncnc34)O2)O)O)O1)O)O))C(N)=O

Properties:
Formula:C21H29N7O14P2Atoms:52
Molecular Weight:665.441Rotatable Bonds:11
H-bond Acceptors:19H-bond Donors:0
logP:-1.467
Targets:
NameUniprot IDSourceReferencesInteraction
11-cis retinol dehydrogenaseRDH1_HUMANDrugBank-shows
15-hydroxyprostaglandin dehydrogenase [NAD+]PGDH_HUMANDrugBank-shows
2-oxoglutarate dehydrogenase E1 component, mitochondrialODO1_HUMANDrugBank-shows
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 13BHS1_HUMANDrugBank-shows
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 23BHS2_HUMANDrugBank-shows
3-hydroxy-3-methylglutaryl-coenzyme A reductaseHMDH_HUMANDrugBank-shows
3-hydroxyacyl-CoA dehydrogenase type-2HCD2_HUMANDrugBank-shows
3-hydroxyisobutyrate dehydrogenase, mitochondrial3HIDH_HUMANDrugBank-shows
3-keto-steroid reductaseDHB7_HUMANDrugBank-shows
4-trimethylaminobutyraldehyde dehydrogenaseAL9A1_HUMANDrugBank-shows
7-dehydrocholesterol reductaseDHCR7_HUMANDrugBank-shows
Acyl carrier protein, mitochondrialACPM_HUMANDrugBank-shows
Alcohol dehydrogenase 1AADH1A_HUMANDrugBank-shows
Alcohol dehydrogenase 1BADH1B_HUMANDrugBank-shows
Alcohol dehydrogenase 1CADH1G_HUMANDrugBank-shows
Alcohol dehydrogenase 4ADH4_HUMANDrugBank-shows
Alcohol dehydrogenase class 4 mu/sigma chainADH7_HUMANDrugBank-shows
Alcohol dehydrogenase class-3ADHX_HUMANDrugBank-shows
Aldehyde dehydrogenase family 1 member A3AL1A3_HUMANDrugBank-shows
Aldehyde dehydrogenase family 3 member B1AL3B1_HUMANDrugBank-shows
Aldehyde dehydrogenase family 3 member B2AL3B2_HUMANDrugBank-shows
Aldehyde dehydrogenase X, mitochondrialAL1B1_HUMANDrugBank-shows
Aldehyde dehydrogenase, dimeric NADP-preferringAL3A1_HUMANDrugBank-shows
Aldehyde dehydrogenase, mitochondrialALDH2_HUMANDrugBank-shows
Aldo-keto reductase family 1 member C1AK1C1_HUMANDrugBank-shows
Aldo-keto reductase family 1 member C2AK1C2_HUMANDrugBank-shows
Aldo-keto reductase family 1 member C3AK1C3_HUMANDrugBank-shows
Aldo-keto reductase family 1 member C4AK1C4_HUMANDrugBank-shows
Aldose reductaseALDR_HUMANDrugBank-shows
Alpha-aminoadipic semialdehyde dehydrogenaseAL7A1_HUMANDrugBank-shows
Alpha-aminoadipic semialdehyde synthase, mitochondrialAASS_HUMANDrugBank-shows
Aminomethyltransferase, mitochondrialGCST_HUMANDrugBank-shows
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrialMTDC_HUMANDrugBank-shows
Biliverdin reductase ABIEA_HUMANDrugBank-shows
C-1-tetrahydrofolate synthase, cytoplasmicC1TC_HUMANDrugBank-shows
C-4 methylsterol oxidaseERG25_HUMANDrugBank-shows
Corticosteroid 11-beta-dehydrogenase isozyme 1DHI1_HUMANDrugBank-shows
Corticosteroid 11-beta-dehydrogenase isozyme 2DHI2_HUMANDrugBank-shows
Cysteine dioxygenase type 1CDO1_HUMANDrugBank-shows
Cytochrome P450 4A11CP4AB_HUMANDrugBank-shows
D-3-phosphoglycerate dehydrogenaseSERA_HUMANDrugBank-shows
D-beta-hydroxybutyrate dehydrogenase, mitochondrialBDH_HUMANDrugBank-shows
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrialAL4A1_HUMANDrugBank-shows
Dihydrofolate reductaseDYR_HUMANDrugBank-shows
Dihydrolipoyl dehydrogenase, mitochondrialDLDH_HUMANDrugBank-shows
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrialODP2_HUMANDrugBank-shows
Dihydropteridine reductaseDHPR_HUMANDrugBank-shows
Estradiol 17-beta-dehydrogenase 1DHB1_HUMANDrugBank-shows
Estradiol 17-beta-dehydrogenase 2DHB2_HUMANDrugBank-shows
Estradiol 17-beta-dehydrogenase 8DHB8_HUMANDrugBank-shows
Fatty aldehyde dehydrogenaseAL3A2_HUMANDrugBank-shows
Flavin reductaseBLVRB_HUMANDrugBank-shows
GDH/6PGL endoplasmic bifunctional proteinG6PE_HUMANDrugBank-shows
GDP-L-fucose synthetaseFCL_HUMANDrugBank-shows
Glutamate dehydrogenase 1, mitochondrialDHE3_HUMANDrugBank-shows
Glutamate dehydrogenase 2, mitochondrialDHE4_HUMANDrugBank-shows
Glutathione reductase, mitochondrialGSHR_HUMANDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenaseG3P_HUMANDrugBank-shows
Glyceraldehyde-3-phosphate dehydrogenase, testis-specificG3PT_HUMANDrugBank-shows
Glycerol-3-phosphate dehydrogenase [NAD+], cytoplasmicGPDA_HUMANDrugBank-shows
Heme oxygenase 1HMOX1_HUMANDrugBank-shows
Heme oxygenase 2HMOX2_HUMANDrugBank-shows
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrialHCDH_HUMANDrugBank-shows
Inosine-5'-monophosphate dehydrogenase 1IMDH1_HUMANDrugBank-shows
Inosine-5'-monophosphate dehydrogenase 2IMDH2_HUMANDrugBank-shows
Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrialIDH3A_HUMANDrugBank-shows
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrialIDH3B_HUMANDrugBank-shows
Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrialIDH3G_HUMANDrugBank-shows
L-lactate dehydrogenase A chainLDHA_HUMANDrugBank-shows
L-lactate dehydrogenase A-like 6ALDH6A_HUMANDrugBank-shows
L-lactate dehydrogenase A-like 6BLDH6B_HUMANDrugBank-shows
L-lactate dehydrogenase B chainLDHB_HUMANDrugBank-shows
L-lactate dehydrogenase C chainLDHC_HUMANDrugBank-shows
Malate dehydrogenase, cytoplasmicMDHC_HUMANDrugBank-shows
Malate dehydrogenase, mitochondrialMDHM_HUMANDrugBank-shows
Methylmalonate-semialdehyde dehydrogenase [acylating], mitochondrialMMSA_HUMANDrugBank-shows
NAD(P) transhydrogenase, mitochondrialNNTM_HUMANDrugBank-shows
NAD-dependent malic enzyme, mitochondrialMAOM_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1NDUA1_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrialNDUAA_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 11NDUAB_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12NDUAC_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13NDUAD_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2NDUA2_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 3NDUA3_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4NDUA4_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4-like 2NUA4L_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5NDUA5_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6NDUA6_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7NDUA7_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8NDUA8_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrialNDUA9_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 1NDUB1_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10NDUBA_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 2, mitochondrialNDUB2_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3NDUB3_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4NDUB4_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrialNDUB5_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 6NDUB6_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7NDUB7_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 8, mitochondrialNDUB8_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9NDUB9_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 subunit C1, mitochondrialNDUC1_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] 1 subunit C2NDUC2_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrialNDUV1_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrialNDUV2_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrialNDUV3_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrialNDUS2_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrialNDUS3_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrialNDUS4_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] iron-sulfur protein 5NDUS5_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrialNDUS6_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] iron-sulfur protein 7, mitochondrialNDUS7_HUMANDrugBank-shows
NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrialNDUS8_HUMANDrugBank-shows
NADH-cytochrome b5 reductase 3NB5R3_HUMANDrugBank-shows
NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrialNDUS1_HUMANDrugBank-shows
NADH-ubiquinone oxidoreductase chain 1NU1M_HUMANDrugBank-shows
NADH-ubiquinone oxidoreductase chain 2NU2M_HUMANDrugBank-shows
NADH-ubiquinone oxidoreductase chain 3NU3M_HUMANDrugBank-shows
NADH-ubiquinone oxidoreductase chain 4NU4M_HUMANDrugBank-shows
NADH-ubiquinone oxidoreductase chain 4LNU4LM_HUMANDrugBank-shows
NADH-ubiquinone oxidoreductase chain 5NU5M_HUMANDrugBank-shows
NADH-ubiquinone oxidoreductase chain 6NU6M_HUMANDrugBank-shows
NADP-dependent malic enzymeMAOX_HUMANDrugBank-shows
NADP-dependent malic enzyme, mitochondrialMAON_HUMANDrugBank-shows
Peroxisomal bifunctional enzymeECHP_HUMANDrugBank-shows
Peroxisomal multifunctional enzyme type 2DHB4_HUMANDrugBank-shows
Pyrroline-5-carboxylate reductase 1, mitochondrialP5CR1_HUMANDrugBank-shows
Pyrroline-5-carboxylate reductase 2P5CR2_HUMANDrugBank-shows
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrialODPA_HUMANDrugBank-shows
Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrialODPAT_HUMANDrugBank-shows
Pyruvate dehydrogenase E1 component subunit beta, mitochondrialODPB_HUMANDrugBank-shows
Retinal dehydrogenase 1AL1A1_HUMANDrugBank-shows
Retinal dehydrogenase 2AL1A2_HUMANDrugBank-shows
Ribosyldihydronicotinamide dehydrogenase [quinone]NQO2_HUMANDrugBank-shows
Short-chain specific acyl-CoA dehydrogenase, mitochondrialACADS_HUMANDrugBank-shows
Sorbitol dehydrogenaseDHSO_HUMANDrugBank-shows
Steroid 17-alpha-hydroxylase/17,20 lyaseCP17A_HUMANDrugBank-shows
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylatingNSDHL_HUMANDrugBank-shows
Succinate-semialdehyde dehydrogenase, mitochondrialSSDH_HUMANDrugBank-shows
Testosterone 17-beta-dehydrogenase 3DHB3_HUMANDrugBank-shows
Trifunctional enzyme subunit alpha, mitochondrialECHA_HUMANDrugBank-shows
TyrosinaseTYRO_HUMANDrugBank-shows
UDP-glucose 6-dehydrogenaseUGDH_HUMANDrugBank-shows
Synonyms:
1,4-Dihydronicotinamide adenine dinucleotide
58-68-4
AC1L96RW
Adenosine 5'-(trihydrogen diphosphate), P'->5'-ester with 1,4-dihydro-1-beta-D-ribofuranosyl-3-pyridinecarboxamide (9CI)
Adenosine 5'-(trihydrogen pyrophosphate), 5'-5'-ester with 1,4-dihydro-1beta-D-ribofuranosylnicotinamide
Adenosine 5'-(trihydrogen pyrophosphate), 5'->5'-ester with 1,4-dihydro-1-beta-D-ribofuranosylnicotinamide (8CI)
adenosine 5'-{3-[1-(3-carbamoyl-1,4-dihydropyridin-1-yl)-1,4-anhydro-D-ribitol-5-yl] dihydrogen diphosphate}
Adenosine pyrophosphate, 5'->5'-ester with 1,4-dihydro-1-beta-D-ribofuranosylnicotinamide (7CI)
beta-DPNH
beta-NADH
bmse000054
C00004
CHEBI:16908
CHEMBL1234616
Codehydrase I, reduced
Codehydrogenase I, reduced
Coenzyme I, reduced
Cozymase I, reduced
DB00157
Dihydrocodehydrogenase I
Dihydrocozymase
dihydrodiphosphopyridine nucleotide
Dihydronicotinamide adenine dinucleotide
Dihydronicotinamide mononucleotide
Diphosphopyridine nucleotide
diphosphopyridine nucleotide reduced
DPN
DPN+
DPNH
NAD
NAD+
NAD-reduced
NADH
NADH+H+
NADH2
NAI
NAJ
NChemBio.2007.9-comp15
Nicotinamide adenine dinucleotide
nicotinamide adenine dinucleotide (reduced)
nicotinamide adenine dinucleotide reduced
Nicotinaminde-Adenine-Dinucleotide
Reduced codehydrogenase I
Reduced diphosphopyridine nucleotide
Reduced Nicotinamide Adenine Dinucleotide
Reduced nicotinamide adenine diphosphate
Reduced nicotinamide-adenine dinucleotide
[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[[(
[(2R,3S,4R,5R)-5-(6-Aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-[[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl]oxy-phosphinic acid
[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl [[(2R,3S,4R,5R)-5-(3-carbamoyl-4H-pyridin-1-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] hydrogen phosphate