Drug Details

Name:

CHEMBL504547

PubChem ID:

42625986

Pathway:

Show KEGG pathways

InChI:

InChI=1S/C21H15IN2O4/c22-14-2-4-16-17(8-14)18(21(27)24-20(16)26)10-23-9-12-1-3-15(19(25)7-12)13-5-6-28-11-13/h1-8,10-11,23,25H,9H2,(H,24,26,27)/b18-10-

SMILES:

Ic1ccc2c(c1)/C(=C/NCc1ccc(c(c1)O)c1ccoc1)/C(=O)NC2=O

Properties:

Formula:	C21H15IN2O4	Atoms:	28
Molecular Weight:	486.259	Rotatable Bonds:	4
H-bond Acceptors:	6	H-bond Donors:	3
logP:	4.3772

Targets:

Name	Uniprot ID	Source	References	Interaction
Cell division protein kinase 2	CDK2_HUMAN	BindingDB	-	shows
Cell division protein kinase 4	CDK4_HUMAN	BindingDB	-	shows
Epidermal growth factor receptor	EGFR_HUMAN	BindingDB	-	shows
Inhibitor of nuclear factor kappa-B kinase subunit beta	IKKB_HUMAN	BindingDB	-	shows
Insulin receptor	INSR_HUMAN	BindingDB	-	shows
MAP kinase-activated protein kinase 2	MAPK2_HUMAN	BindingDB	-	shows
Protein kinase C theta type	KPCT_HUMAN	BindingDB	-	shows
Proto-oncogene tyrosine-protein kinase LCK	LCK_HUMAN	BindingDB	-	shows
Proto-oncogene tyrosine-protein kinase Src	SRC_HUMAN	BindingDB	-	shows
RAC-alpha serine/threonine-protein kinase	AKT1_HUMAN	BindingDB	-	shows
Retinoblastoma-associated protein	RB_HUMAN	BindingDB	-	shows
Vascular endothelial growth factor receptor 2	VGFR2_HUMAN	BindingDB	-	shows

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Synonyms:

CHEBI:598560

CHEMBL504547

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