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Drug Details

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Name:Ritonavir
PubChem ID:392622
Pathway:Show KEGG pathways
InChI:InChI=1/C37H48N6O5S2/c1-24(2)33(42-36(46)43(5)20-29-22-49-35(40-29)25(3)4)34(45)39-28(16-26-12-8-6-9-13-26)18-32(44)31(17-27-14-10-7-11-15-27)41-37(47)48-21-30-19-38-23-50-30/h6-15,19,22-25,28,31-33,44H,16-18,20-21H2,1-5H3,(H,39,45)(H,41,47)(H,42,46)/t28-,31-,32-,33-/m0/s1/f/h39,41-42H
SMILES:CC(C)[C@@H](C(N[C@@H](Cc1ccccc1)(C[C@H]([C@@H](Cc1ccccc1)NC(=O)OCc1cncs1)O))=O)NC(N(C)Cc1csc(C(C)C)n1)=O

Properties:
Formula:C37H48N6O5S2Atoms:54
Molecular Weight:720.944Rotatable Bonds:22
H-bond Acceptors:10H-bond Donors:0
logP:7.0779
Targets:
Synonyms:
1,3-thiazol-5-ylmethyl N-[(2S,3S,5S)-3-hydroxy-5-[[(2S)-3-methyl-2-[[methyl-[(2-propan-2-yl-1,3-thiazol-4-yl)methyl]carbamoyl]amino]butanoyl]amino]-1,6-di(phenyl)hexan-2-yl]carbamate
155213-67-5
1hxw
1sh9
2,4,7,12-Tetraazatridecan-13-oic acid, 10-hydroxy-2-methyl-5-(1-methylethyl)-1-(2-(1-methylethyl)-4-thiazolyl)-3,6-dioxo-8,11-bis(phenylmethyl)-, 5-thiazolylmethyl ester, (5S-(5R*,8R*,10R*,11R*))-
2,4,7,12-Tetraazatridecan-13-oic acid, 10-hydroxy-2-methyl-5-(1-methylethyl)-1-[2-(1-methylethyl)-4-thiazolyl]-3,6-dioxo-8,11-bis(phenylmethyl)-, 5-thiazolylmethyl ester, [5S-(5R*,8R*,10R*,11R*)]-
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S)-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
5-Thiazolylmethyl ((alphaS)-alpha-((1S,3S-1-hydroxy-3-((2S)-2-(3-((2-isopropyl-4-thiazolyl)methyl)-3-methylureido)-3-methylbutyramido)-4-phenylbutyl)phenethyl)carbamate
A-84538
Abbott 84538
ABT 84538
ABT-538
ABT538
AIDS-028478
AIDS028478
C07240
C37H48N6O5S2
Component of Kaletra
CPD000466395
D00427
DB00503
DRG-0244
HSDB 7160
KALETRA
LS-148860
Mixture Name
MLS000759541
MLS001424063
NCGC00159462-02
Norvir
Norvir (TM)
Norvir (TN)
Norvir Sec
NSC693184
RIT
Ritonavir
Ritonavir (JAN/USAN/INN)
Ritonavir is an inhibitor of HIV protease used to treat HIV infection and
Ritonavir [USAN]
RTV
SAM001246783
SMR000466395
STOCK6S-48483
ZINC03944422
ATC-Codes: