Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug Details

add
Name:Letrozole
PubChem ID:3902
Pathway:Show KEGG pathways
InChI:InChI=1/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H
SMILES:c1cc(ccc1C#N)C(c1ccc(cc1)C#N)n1cncn1

Properties:
Formula:C17H11N5Atoms:22
Molecular Weight:285.303Rotatable Bonds:3
H-bond Acceptors:4H-bond Donors:0
logP:2.65916
Targets:
Synonyms:
1-[bis(4-cyanophenyl)methyl]-1,2,4-triazole
1-[Bis-(4-cyanophenyl)methyl]-1,2,4-triazole
112809-51-5
4,4'-((1h-1,2,4-triazol-1-yl)methylene)dibenzonitrile
4,4'-(1H-1,2,4-triazol-1-yl-methylene)-bis(benzonitrile)
4,4'-(1H-1,2,4-triazol-1-ylmethanediyl)dibenzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene) bis-benzonitrile
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bis-benzonitrile
4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-Benzonitrile Letrozole
4,4'-(1h-1,2,4-triazol-1-ylmethylene)bisbenzonitrile
4,4'-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
4-[(4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile
AB00514009
AC-1193
AC1L1GYT
AKOS005145822
Benzonitrile, 4,4'-(1H-1,2,4-triazol-1-ylmethylene)bis-
BIDD:GT0015
BIDD:PXR0130
Bio-0057
BPBio1_001331
BRD-K88789588-001-03-2
BSPBio_001209
C067431
C08163
C17H11N5
CAS-112809-51-5
CCG-100849
CCRIS 8822
CGS 20267
CGS 20267, Femara, Piroxicam, Letrozole
CGS-20267
CHEBI:6413
CHEMBL1444
CPD000466343
D00964
DB01006
F?mara
FEM-345
Femara
Femara (TN)
Femera
HMS1571M11
HMS2051E08
HMS2089L22
HMS2098M11
HMS2233C23
HSDB 7461
I06-0022
Letoval
Letrozol
Letrozole
Letrozole (JAN/USP/INN)
Letrozole [USAN:INN]
Letrozole-Supplied by Selleck Chemicals
LS-38788
MLS000759455
MLS001424038
MLS002584991
NCGC00016973-01
NCGC00016973-02
NCGC00016973-03
Novartis Brand of Letrozole
NSC719345
Prestwick0_001025
Prestwick1_001025
Prestwick2_001025
Prestwick3_001025
S1235_Selleck
SAM001246649
SMR000466343
SPBio_003070
STOCK6S-51833
TL8000371
UNII-7LKK855W8I
ZINC03778874
ATC-Codes:
Side-Effects:
Side-EffectFrequency
hot flashes0.22453468
bone pain0.22
back pain0.18
weakness0.12444443
flushes0.12335023
arthritis0.11661485
nausea0.114906915
dyspnea0.10888889
arthralgia0.108307414
influenza0.10666667
weight decreased0.10333333
pain in limb0.1
night sweats0.094044
vascular disorders0.09
fatigue0.080135845
headache0.07149914
urinary tract infection0.071428575
breast pain0.07
lymphedema0.07
insomnia0.07
coughing0.06666667
chest pain0.063846156
constipation0.06325521
hypertension0.061818182
chest wall pain0.06
edema peripheral0.058000006
viral infection0.055000003
diarrhea0.054615382
weight increase0.051577892
pain0.049384616
vomiting0.04799371
asthenia0.044203773
malaise0.04300944
rash0.04125
dyspepsia0.04125
anorexia0.04
edema0.03655189
dizziness0.03578354
myalgia0.035422947
somnolence0.024999999
pruritus0.02375
vaginal bleeding0.022757862
hypercholesterolemia0.018
osteoporosis0.010845907
cancer0.0069999998
angina0.005517295
myocardial infarction0.00401677
endometrial cancer0.0020
cardiac failure0.0010
blurred vision0.0010
stomatitis0.0010
tachycardia0.0010
urticaria0.0010
palpitations0.0010
pyrexia0.0010
urinary frequency0.0010
leukopenia0.0010
vaginal discharge0.0010
cataract0.0010
dysaesthesia0.0010
dry mouth0.0010
nervousness0.0010
paraesthesia0.0010
arm pain0
portal vein thrombosis0
memory impairment0
increased sweating0
venous thrombosis0
vertigo0
myocardial ischemia0
thrombophlebitis0
infection0
hypercalcemia0
hemorrhage0
hemiparesis0
heart disease0
abdominal pain0
constitutional symptoms0
connective tissue disorders0
breast disorders0
anxiety0
irritability0
nephropathy0
sweating0
cerebrovascular accident0
pulmonary embolism0
pleural effusion0
phlebitis0
tumor0
transient ischemic attack0
musculoskeletal pain0
mediastinal disorders0
leg pain0
alopecia0