Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug Details

add
Name:Haloperidol
PubChem ID:3559
Pathway:Show KEGG pathways
InChI:InChI=1/C21H23ClFNO2/c22-18-7-5-17(6-8-18)21(26)11-14-24(15-12-21)13-1-2-20(25)16-3-9-19(23)10-4-16/h3-10,26H,1-2,11-15H2
SMILES:C(CC(c1ccc(cc1)F)=O)CN1CCC(CC1)(c1ccc(cc1)Cl)O

Properties:
Formula:C21H23ClFNO2Atoms:26
Molecular Weight:375.864Rotatable Bonds:6
H-bond Acceptors:4H-bond Donors:0
logP:4.3635
Targets:
NameUniprot IDSourceReferencesInteraction
5-hydroxytryptamine receptor 1A5HT1A_HUMANBindingDB-shows
5-hydroxytryptamine receptor 2A5HT2A_HUMANBindingDB-shows
5-hydroxytryptamine receptor 2C5HT2C_HUMANBindingDB-shows
5-hydroxytryptamine receptor 65HT6R_HUMANBindingDB-shows
Adenylate cyclase type 10ADCYA_RABITPROMISCUOUSPMID 192161shows
Adenylate cyclase type 5ADCY5_RABITPROMISCUOUSPMID 192161shows
Aldo-keto reductase family 1 member C1AK1C1_HUMANSuperTargetPMID 010609553shows
Alpha-1D adrenergic receptorADA1D_HUMANBindingDB-shows
Alpha-2C adrenergic receptorADA2C_HUMANBindingDB-shows
Cytochrome P450Q7Z448_HUMANSuperTargetPMID 009681669shows
Cytochrome P450Q86SK2_HUMANSuperTargetPMID 009681669shows
Cytochrome P450Q86SK3_HUMANSuperTargetPMID 009681669shows
Cytochrome P450 1A1CP1A1_HUMANSuperCypPMID 11717183shows
Cytochrome P450 1A2CP1A2_HUMANSuperCyp-shows
Cytochrome P450 2C19CP2CJ_HUMANSuperCypPMID 11717183shows
Cytochrome P450 2C9CP2C9_HUMANSuperCypPMID 11717183shows
Cytochrome P450 2D6CP2D6_HUMANSuperCypPMID 10460810shows
Cytochrome P450 3A4CP3A4_HUMANSuperCyp-shows
Cytochrome P450 3A5CP3A5_HUMANSuperCypPMID 11717183shows
Cytochrome P450 3A7CP3A7_HUMANSuperCyp-shows
Cytochrome P450 CYP3A4Q9BZM0_HUMANSuperTargetPMID 009681669shows
Cytochrome P450 family 3 subfamily A polypeptide 4Q6GRK0_HUMANSuperTargetPMID 009681669shows
D(1A) dopamine receptorDRD1_HUMANBindingDB-shows
D(1B) dopamine receptorDRD5_HUMANBindingDB-shows
D(2) dopamine receptorDRD2_HUMANBindingDB-shows
D(2) dopamine receptorDRD2_RATBindingDB-shows
D(3) dopamine receptorDRD3_HUMANBindingDB-shows
D(4) dopamine receptorDRD4_HUMANBindingDB-shows
Dopamine D2 receptorQ6LDH7_HUMANSuperTargetPMID 016343652shows
Dopamine receptor D2 isoform long variantQ59EH9_HUMANSuperTargetPMID 016343652shows
Glutamate receptor, ionotropic, N-methyl D-aspartate 1Q5VSF4_HUMANSuperTargetPMID 008967976shows
Glutamate receptor, ionotropic, N-methyl D-aspartate 1Q5VSF5_HUMANSuperTargetPMID 008967976shows
Glutamate receptor, ionotropic, N-methyl D-aspartate 1Q5VSF9_HUMANSuperTargetPMID 008967976shows
Glutamate [NMDA] receptor subunit 3ANMD3A_RATBindingDB-shows
Glutamate [NMDA] receptor subunit epsilon-2NMDE2_HUMANDrugBank-shows
Glutamate [NMDA] receptor subunit zeta-1NMDZ1_HUMANSuperTargetPMID 008967976shows
Histamine H1 receptorHRH1_HUMANBindingDB-shows
L-xylulose reductaseDCXR_HUMANSuperTargetPMID 001755933shows
Major prion proteinPRIO_HUMANBindingDB-shows
Multidrug resistance protein 1MDR1_HUMANBindingDB-shows
Muscarinic acetylcholine receptor M1ACM1_HUMANBindingDB-shows
NMDA receptor 1 isoform NR1-2 variantQ59H41_HUMANSuperTargetPMID 008967976shows
NMDAR1 subunit isoform 3bQ9UPF9_HUMANSuperTargetPMID 008967976shows
NMDAR1 subunit isoform 4bQ9UPF8_HUMANSuperTargetPMID 008967976shows
Potassium voltage-gated channel subfamily H member 2KCNH2_HUMANBindingDB-shows
Sodium-dependent serotonin transporterSC6A4_HUMANBindingDB-shows
Synonyms:
.gamma.-[4-(p-Chlorphenyl)-4-hydroxpiperidino]-p-fluorbutyrophenone
1-(3-p-Fluorobenzoylpropyl)-4-p-chlorophenyl-4-hydroxypiperidine
1-Butanone, 4-(4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-
1-Butanone, 4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-
4'-Fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidinyl)butyrophenone
4'-Fluoro-4-(4-hydroxy-4-(4'-chlorophenyl)piperidino)butyrophenone
4'-Fluoro-4-(4-hydroxy-4-p-chlorophenylpiperidino)butyrophenone
4'-Fluoro-4-[4-hydroxy-4-(4'-chlorophenyl)piperidino]butyrophenone
4-(4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl)-1-(4-fluorophenyl)-1-butanone
4-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone
4-(4-(para-chlorophenyl)-4-hydroxypiperidino)-4'-fluorobutyrophenone
4-(4-Hydroxy-4'-chloro-4-phenylpiperidino)-4'-fluorobutyrophenone
4-[4-(4-Chlorophenyl)-4-hydroxy-1-piperidinyl]-1-(4-fluorophenyl)-1-butanone
4-[4-(4-chlorophenyl)-4-hydroxy-1-piperidyl]-1-(4-fluorophenyl)-butan-1-one
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-o
4-[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-1-(4-fluorophenyl)butan-1-one
4-[4-(4-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone
4-[4-(p-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone
4-[4-(para-Chlorophenyl)-4-hydroxypiperidino]-4'-fluorobutyrophenone
5-21-02-00377 (Beilstein Handbook Reference)
52-86-8
AB00052008
AIDS-001623
AIDS001623
Aldo
Aloperidin
Aloperidol
Aloperidolo
Aloperidolo [DCIT]
Aloperidolo [Italian]
Aloperidon
Biomol-NT_000035
BPBio1_000144
BPBio1_001231
BRN 0331267
Brotopon
BSPBio_000130
BSPBio_002096
Butyrophenone, 4'-fluoro-4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-
Butyrophenone, 4-(4-(p-chlorophenyl)-4-hydroxypiperidino)-4'-fluoro-
Butyrophenone, 4-[4-(p-chlorophenyl)-4-hydroxypiperidino]-4'-fluoro-
C01814
C21H23ClFNO2
CAS-52-86-8
CCRIS 1630
CHEBI:5613
CID3559
cMAP_000037
D00136
D006220
DB00502
DivK1c_000654
Dozic
Einalon S
EINECS 200-155-6
EU-0100583
Eukystol
Fortunan
Galoperidol
gamma-(4-(p-chlorophenyl)-4-hydroxpiperidino)-p-fluorbutyrophenone
gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorbutyrophenone
gamma-(4-(p-Chlorophenyl)-4-hydroxypiperidino)-p-fluorobutyrophenone
H1512_SIGMA
Haldol
Haldol (TN)
HALDOL SOLUTAB
Halojust
Halol
Halopal
Haloperidol
Haloperidol (JP15/USP/INN)
Haloperidol [USAN:BAN:INN:JAN]
Haloperidol [USAN:INN:BAN:JAN]
Haloperidolum
Haloperidolum [INN-Latin]
Halopoidol
HSDB 3093
IDI1_000654
IN1474
KBio1_000654
KBio2_001341
KBio2_002390
KBio2_003909
KBio2_004958
KBio2_006477
KBio2_007526
KBio3_001316
KBio3_002869
KBioGR_000980
KBioGR_002390
KBioSS_001341
KBioSS_002395
Keselan
Lealgin compositum
Linton
Lopac-H-1512
Lopac0_000583
LS-48311
McN-JR-1625
Mixidol
MLS000028450
MLS001146904
NCGC00015500-01
NCGC00015500-02
NCGC00016234-01
NCGC00023875-02
NCGC00023875-04
NCGC00023875-05
NCGC00023875-06
NCGC00023875-07
NCGC00023875-08
NCGC00023875-09
NINDS_000654
NSC 170973
NSC 615296
NSC170973
NSC615296
Oprea1_509923
Peluces
Pernox
Prestwick0_000115
Prestwick1_000115
Prestwick2_000115
Prestwick3_000115
Prestwick_250
Probes1_000255
Probes2_000296
QTL1_000042
R 1625
R-1625
Serenace
Serenase
Serenelfi
Sernas
Sernel
SMR000058303
SPBio_001236
SPBio_002069
SPECTRUM1500325
Spectrum2_001268
Spectrum3_000448
Spectrum4_000570
Spectrum5_000788
Spectrum_000861
ST5319916
Tocris-0931
Ulcolind
Uliolind
Vesalium
WLN: T6NTJ A3VR DF& DQ DR DG
ATC-Codes:
Side-Effects:
Side-EffectFrequency
insomnia0
cerebrovascular accident0
spasm0
increased salivation0
seizures0
retinopathy0
priapism0
nausea0
breast pain0
leukopenia0
leukocytosis0
jaundice0
tachycardia0
vertigo0
increased sweating0
tardive dyskinesia0
photosensitivity0
blurred vision0
parkinson0
drug withdrawal0
cataract0
agitation0
urinary retention0
dry mouth0
vomiting0
impotence0
hypotension0
somnolence0
diarrhea0
dysphagia0
constipation0
confusion0
bronchospasm0
arrhythmia0
anxiety0
anorexia0
anemia0
alopecia0
dyskinesia0
dyspepsia0
hyponatremia0
hypoglycemia0
hypertension0
hyperglycemia0
headache0
hallucinations0
gynecomastia0
euphoria0
grand mal0
endocrine disorders0
dyspnea0
agranulocytosis0