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Drug Details

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Name:Fasudil hydrochloride
PubChem ID:3547
Pathway:Show KEGG pathways
InChI:InChI=1/C14H17N3O2S/c18-20(19,17-9-2-6-15-8-10-17)14-4-1-3-12-11-16-7-5-13(12)14/h1,3-5,7,11,15H,2,6,8-10H2
SMILES:c1cc2cnccc2c(c1)S(N1CCCNCC1)(=O)=O

Properties:
Formula:C14H17N3O2SAtoms:20
Molecular Weight:291.369Rotatable Bonds:2
H-bond Acceptors:5H-bond Donors:0
logP:2.5663
Targets:
NameUniprot IDSourceReferencesInteraction
Beta-lactamaseAMPC_ECOLIBindingDB-shows
cAMP-dependent protein kinase catalytic subunit alphaKAPCA_MOUSEBindingDB-shows
cAMP-dependent protein kinase catalytic subunit alphaKAPCA_HUMANPROMISCUOUSPMID 16249185shows
cAMP-dependent protein kinase catalytic subunit betaKAPCB_HUMANPROMISCUOUSPMID 16249185shows
cAMP-dependent protein kinase catalytic subunit gammaKAPCG_HUMANPROMISCUOUSPMID 16249185shows
Dual oxidase 1DUOX1_RATPROMISCUOUSPMID 17511984shows
Dual oxidase 2DUOX2_RATPROMISCUOUSPMID 17511984shows
GTP binding proteinQ06976_HUMANPROMISCUOUSPMID 10233893shows
GTP binding proteinQ8NG23_HUMANPROMISCUOUSPMID 10233893shows
GTP-binding proteinQ96QB8_HUMANPROMISCUOUSPMID 10233893shows
Interstitial collagenaseMMP1_HUMANPROMISCUOUSPMID 15998434shows
Nitric oxide synthaseQ62710_RATPROMISCUOUSPMID 11553365shows
Nitric oxide synthase, brainNOS1_MOUSEPROMISCUOUSPMID 17204906shows
Nitric oxide synthase, brainNOS1_RATPROMISCUOUSPMID 17111028shows
Nitric oxide synthase, endothelialNOS3_MOUSEPROMISCUOUSPMID 17204906shows
Nitric oxide synthase, endothelialNOS3_RATPROMISCUOUSPMID 17111028shows
Nitric oxide synthase, inducibleNOS2_MOUSEPROMISCUOUSPMID 17204906shows
Nitric oxide synthase, inducibleNOS2_RATPROMISCUOUSPMID 17111028shows
Protein kinase CKPC3_DROMEPROMISCUOUSPMID 15459803shows
Protein kinase CKPC1_LYTPIPROMISCUOUSPMID 15459803shows
Protein kinase cB8LXH5_TALSNPROMISCUOUSPMID 15459803shows
Protein kinase C epsilon typeKPCE_HUMANBindingDB-shows
RAC-alpha serine/threonine-protein kinaseAKT1_MOUSEPROMISCUOUSPMID 17204906shows
Rho-associated protein kinase 1ROCK1_HUMANSuperTarget-shows
Ribosomal protein S6 kinase alpha-5KS6A5_HUMANBindingDB-shows
Synonyms:
(5-ISOQUINOLINESULFONYL)HOMOPIPERAZINE
1-(5-Isoquinolinesulfonyl)homopiperazine
1-(5-Isoquinolinesulphonyl)homopiperazine
1-(5-Isoquinolinylsulfonyl)homopiperazine
1-(5-Isoquinolylsulfonyl)-1,4-diazaperhydroepine
103745-39-7
105628-07-7
105628-07-7(HYDROCHLORIDE)
1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)-
1H-1,4-Diazepine, hexahydro-1-(5-isoquinolinylsulfonyl)- (9CI)
1q8w
2esm
2gni
5-(1,4-DIAZEPAN-1-SULFONYL)ISOQUINOLINE
5-(1,4-diazepan-1-ylsulfonyl)isoquinoline
5-(1,4-diazepane-1-sulfonyl)isoquinoline
AC1L1G6K
AC1Q6UWJ
AC1Q6VJ2
AIDS-108016
AIDS108016
AR-1A6371
AT 877
AT-877
AT877
Bio2_000386
Bio2_000866
BiomolKI2_000046
BiomolKI_000038
BRD-K76617868-001-02-2
BRD-K76617868-001-03-0
BRD-K76617868-300-03-6
BRD-K76617868-300-04-4
BSPBio_001111
C14H17N3O2S
CCG-100642
CHEMBL38380
D07941
DB08162
Eril
Fasudil
Fasudil (HA-1077)
Fasudil (INN)
Fasudil hydrochloride
Fasudil [INN]
Fasudilum
Fasudilum [INN-Latin]
FH
HA 1077
HA-1077
HA1077
Hexahydro-1-(5-isoquinolinylsulfonyl)-1H-1,4-diazepine
Hexahydro-1-(5-isoquinolylsulfonyl)-1H-1,4-diazepine
HMS1362G13
HMS1792G13
HMS1990G13
HMS2089F13
HMS3264M10
I06-1557
IDI1_002141
KBio2_000451
KBio2_003019
KBio2_005587
KBio3_000841
KBio3_000842
KBioGR_000451
KBioSS_000451
Kinome_3390
Kinome_3391
KST-1A0465
LS-60220
M77
NCGC00018100-01
NCGC00018100-02
NCGC00018100-03
NCGC00018100-04
NCGC00018100-05
NCGC00018100-06
NCGC00018100-07
NCGC00024299-02
NCGC00024299-04
NCGC00024299-05
SMP2_000083
ST51053125
Tocris-0541
UNII-Q0CH43PGXS
ATC-Codes: