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Drug Details

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Name:Glybenzcyclamide
PubChem ID:3488
Pathway:Show KEGG pathways
InChI:InChI=1/C23H28ClN3O5S/c1-32-21-12-9-17(24)15-20(21)22(28)25-14-13-16-7-10-19(11-8-16)33(30,31)27-23(29)26-18-5-3-2-4-6-18/h7-12,15,18H,2-6,13-14H2,1H3,(H,25,28)(H2,26,27,29)/f/h25-27H
SMILES:COc1ccc(cc1C(NCCc1ccc(cc1)S(NC(NC1CCCCC1)=O)(=O)=O)=O)Cl

Properties:
Formula:C23H28ClN3O5SAtoms:33
Molecular Weight:494.004Rotatable Bonds:11
H-bond Acceptors:8H-bond Donors:0
logP:5.8952
Targets:
NameUniprot IDSourceReferencesInteraction
ATP-binding cassette sub-family A member 1ABCA1_HUMANDrugBank-shows
ATP-binding cassette transporter sub-family C member 8ABCC8_HUMANSuperTargetPMID 016418275shows
ATP-binding cassette transporter sub-family C member 9ABCC9_HUMANDrugBank-shows
ATP-sensitive inward rectifier potassium channel 1IRK1_HUMANSuperTargetPMID 14592811shows
ATP-sensitive inward rectifier potassium channel 11IRK11_HUMANDrugBank-shows
Bile salt export pumpABCBB_HUMANDrugBank-shows
Canalicular multispecific organic anion transporter 2MRP3_HUMANDrugBank-shows
CF proteinQ16049_HUMANSuperTargetPMID 015711774shows
Chymotrypsinogen ACTRA_BOVINBindingDB-shows
Cystic fibrosis transmembrane conductance regulatorCFTR_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KE95_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEA0_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEA5_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEB2_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEB8_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEC3_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEC8_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KED3_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KED8_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEE3_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEE7_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEF5_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEF9_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEG3_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEG6_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEG9_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEH3_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEH6_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEH8_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEH9_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEI2_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEI7_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEI8_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEJ1_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEJ4_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ6KEJ7_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ9UJ19_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulatorQ9UML7_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulator ATP-binding cassette subfamily C member 7Q5I6F9_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulator ATP-binding cassette subfamily C member 7Q5I6N4_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulator ATP-binding cassette subfamily C member 7Q5I6N5_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulator ATP-binding cassette subfamily C member 7Q5I6N6_HUMANSuperTargetPMID 015711774shows
Cystic fibrosis transmembrane conductance regulator ATP-binding cassette subfamily C member 7Q5I6N7_HUMANSuperTargetPMID 015711774shows
Cytochrome P450 2C19CP2CJ_HUMANSuperCypPMID 16198656shows
Cytochrome P450 2C9CP2C9_HUMANSuperCypPMID 16198656shows
Cytochrome P450 3A4CP3A4_HUMANSuperCypPMID 15370958shows
G protein-activated inward rectifier potassium channel 4IRK5_HUMANDrugBank-shows
Malate dehydrogenase, cytoplasmicMDHC_HUMANBindingDB-shows
Multidrug resistance-associated protein 1MRP1_HUMANDrugBank-shows
Nuclear receptor subfamily 1 group I member 2NR1I2_MOUSEPROMISCUOUSPMID 12206849shows
Potassium voltage-gated channel subfamily H member 2KCNH2_HUMANBindingDB-shows
Putative uncharacterized protein CFTRQ99989_HUMANSuperTargetPMID 015711774shows
Putative uncharacterized protein CFTRQ9UMN4_HUMANSuperTargetPMID 015711774shows
Sulfonylurea receptor 1 variantQ59GM5_HUMANSuperTargetPMID 016418275shows
Thromboxane A2 receptorTA2R_HUMANSuperTargetPMID 007965789shows
TNR-CFTR proteinQ99904_HUMANSuperTargetPMID 015711774shows
Synonyms:
1-((p-(2-(5-Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylur
1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
10238-21-8
5-Chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide
5-chloro-N-(2-{4-[(cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide
5-chloro-N-(2-{4-[N-(N-cyclohexylcarbamoyl)sulfamoyl]phenyl}ethyl)-2-methoxybenzamide
5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide
AB00051949
Adiab
Apo-Glibenclamide
Azuglucon
Bastiverit
Benclamin
Benzamide, 5-chloro-N-(2-(4-((((cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxy-
Benzamide, 5-chloro-N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-2-methoxy-
Betanase
Betanese 5
Bio1_000076
Bio1_000565
Bio1_001054
Bio2_000071
Bio2_000551
BPBio1_000344
BRN 2230085
BSPBio_000312
BSPBio_001351
BSPBio_003053
C07022
C23H28ClN3O5S
Calabren
CAS-10238-21-8
CBiol_001790
CHEBI:5441
Cytagon
D00336
D005905
Daonil
DB01016
Debtan
Diabeta
Diabeta (TN)
Dibelet
DivK1c_000481
Duraglucon
EINECS 233-570-6
EU-0100499
Euclamin
Euglucan
Euglucon
Euglucon 5
Euglucon N
Euglykon
G0639_SIAL
G0639_SIGMA
G2539_SIAL
GBN 5
Gen-Glybe
Gewaglucon
Gilemal
Glamide
Gliban
Gliben
Glibenbeta
Glibenclamid AL
Glibenclamid Basics
Glibenclamid Fabra
Glibenclamid Genericon
Glibenclamid Heumann
Glibenclamid Riker M
Glibenclamid Riker M.
Glibenclamid-Cophar
Glibenclamid-Ratiopharm
Glibenclamida
Glibenclamida [INN-Spanish]
Glibenclamide
Glibenclamide (JP15/INN)
Glibenclamidum
Glibenclamidum [INN-Latin]
Glibenil
Glibens
Glibesyn
Glibet
Glibetic
Glibil
Gliboral
Glicem
Glidiabet
Glimel
Glimide
Glisulin
Glitisol
Glubate
Gluben
Glucobene
Glucohexal
Glucolon
Glucomid
Glucoremed
GLUCOVANCE
Glucoven
Glyben
Glybenclamide
Glybenzcyclamide
Glyburide
GLYBURIDE (MICRONIZED)
Glyburide (USP)
Glyburide [USAN]
Glycomin
Glynase
Glynase (TN)
HB 419
HB 420
HB-419
HB-420
HB419
HB420
Hemi-Daonil
Hexaglucon
Humedia
IDI1_000481
IDI1_033821
KBio1_000481
KBio2_000071
KBio2_000730
KBio2_002639
KBio2_003298
KBio2_005207
KBio2_005866
KBio3_000141
KBio3_000142
KBio3_002273
KBioGR_000071
KBioGR_001897
KBioSS_000071
KBioSS_000730
Lederglib
Libanil
Lisaglucon
Lopac-G-0639
Lopac0_000499
LS-159295
Maninil
Med-Glionil
Melix
Micronase
Micronase (TN)
Miglucan
MLS000069721
MLS001077262
N-(4-(2-(5-Chloro-2-methoxybenzamido)ethyl)phenylsulfonyl)-N'-cyclohexylurea
N-(4-(beta-(2-Methoxy-5-chlorbenzamido)-aethyl)-benzolsulfonyl)-N'-cyclohexyl-harnstoff
N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N'-cyclohexylurea
Nadib
NCGC00015467-01
NCGC00015467-02
NCGC00016689-01
NCGC00023447-02
NCGC00023447-04
NCGC00023447-05
NCGC00023447-06
NCGC00023447-07
NCGC00023447-08
NCGC00023447-09
NCGC00023447-10
NCGC00023447-11
NCGC00023447-12
Neogluconin
NINDS_000481
Norglicem 5
Normoglucon
Novo-Glyburide
Oprea1_764617
Orabetic
Pira
Praeciglucon
Prestwick0_000316
Prestwick1_000316
Prestwick2_000316
Prestwick3_000316
Prestwick_569
Probes1_000431
Probes2_000378
Prodiabet
Renabetic
Semi-daonil
Semi-Euglucon
Semi-Gliben-Puren N
SMR000058229
SPBio_001831
SPBio_002531
SPECTRUM2300229
Spectrum2_001816
Spectrum3_001327
Spectrum4_001199
Spectrum5_001631
Spectrum_000250
SR-01000000196-5
ST024780
STK362992
Sugril
Suraben
Tiabet
Tocris-0911
U 26452
UPCMLD-DP006
UPCMLD-DP006:001
UR 606
Urea, 1-((p-(2-(chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexyl-
Urea, 1-(p-(2-(5-chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexyl-
Yuglucon
ZINC00537805
ATC-Codes:
Side-Effects:
Side-EffectFrequency
abdominal pain0
pancytopenia0
porphyria0
pruritus0
purpura0
shock0
thrombocytopenia0
erythema0
urticaria0
vasculitis0
vomiting0
hepatic failure0
leukocytoclastic vasculitis0
malnutrition0
porphyria cutanea tarda0
myalgia0
blurred vision0
photosensitivity0
nausea0
leukopenia0
agranulocytosis0
anemia0
aplastic anemia0
hemolytic anemia0
angioedema0
arthralgia0
asthenia0
diarrhea0
dyspnea0
heartburn0
hepatitis0
hyponatremia0
hypopituitarism0
hypotension0
siadh0
jaundice0
nephropathy0
allergic reaction0