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Drug Details

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Name:Clobetasol
PubChem ID:32798
Pathway:Show KEGG pathways
InChI:InChI=1/C25H32ClFO5/c1-5-21(31)32-25(20(30)13-26)14(2)10-18-17-7-6-15-11-16(28)8-9-22(15,3)24(17,27)19(29)12-23(18,25)4/h8-9,11,14,17-19,29H,5-7,10,12-13H2,1-4H3/t14-,17-,18-,19-,22-,23-,24-,25-/m0/s1
SMILES:CCC(=O)O[C@@]1([C@@H](C)(C[C@@H]2([C@@H]3(CCC4=CC(C=C[C@]4(C)[C@@]3([C@@H](C[C@]12C)O)F)=O))))C(CCl)=O

Properties:
Formula:C25H32ClFO5Atoms:36
Molecular Weight:466.97Rotatable Bonds:5
H-bond Acceptors:6H-bond Donors:0
logP:4.1031
Targets:
Synonyms:
21-chloro-9-fluoro-11 beta-hydroxy-16 beta-methylpregna-1,4-diene-3,20-dione 17-propionate
21-Chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione (11beta,16beta)-
21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-
21-Chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
21-Chloro-9-fluoro-11beta-hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17-propionate
25122-46-7
C25H32ClFO5
C8037_FLUKA
C8037_SIGMA
CCI 4725
CGP 9555
CHEBI:31414
Clobesol
Clobetasol
Clobetasol 17-propionate
CLOBETASOL PROPIONATE
CLOBETASOL PROPIONATE (EMOLLIENT)
Clobetasol propionate (JAN/USP)
Clobetasol propionate [USAN:JAN]
Clobex
Clobex (TN)
Cormax
Cormax (TN)
D01272
DB01013
Dermovate
EINECS 246-634-3
EMBELINE
EMBELINE E
GR 2/925
LS-118433
Luxiq
MLS000028708
MLS001076345
Olux
Olux (TN)
OLUX FOAM
Olux-E
Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-methyl-, 17-propionate
Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-beta,17-dihydroxy-16-beta-methyl-,17-propionate
Pregna-1,4-diene-3,20-dione, 21-chloro-9-fluoro-11-hydroxy-16-methyl-17-(1-oxopropoxy)-, (11beta,16beta)-
SMR000058745
Temovate
Temovate E
ZINC03977767
[(8S,9R,10S,11S,13S,14S,16S,17R)-17-(2-chloroacetyl)-9-fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate
ATC-Codes:
Side-Effects:
Side-EffectFrequency
infections0.1
pruritus0.0708661
nasopharyngitis0.025
influenza0.0166667
upper respiratory tract infection0.0166667
pain0.0166667
headache0.00787402
pharyngitis streptococcal0.0
eczema0.0
dry skin0
pyoderma0
rosacea0
hypopigmentation0
telangiectasia0
hyperpigmentation0
striae0
tooth disorder0
erythema0
skin irritation0
urticaria0
burning sensation0
peripheral edema0
skin atrophy0
acne0
pharyngitis0
connective tissue disorders0
delusions0
dermatitis0
atopic dermatitis0
edema0
enteritis0
folliculitis0
gastroenteritis0
glycosuria0
hyperglycemia0
hypersensitivity0
hypertrichosis0
miliaria0
numbness0
contact dermatitis0
pain in limb0
alopecia0