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Drug Details

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Name:Telithromycin
PubChem ID:3002190
Pathway:-
InChI:InChI=1/C43H65N5O10/c1-12-33-43(8)37(48(41(53)58-43)19-14-13-18-47-23-31(45-24-47)30-16-15-17-44-22-30)27(4)34(49)25(2)21-42(7,54-11)38(28(5)35(50)29(6)39(52)56-33)57-40-36(51)32(46(9)10)20-26(3)55-40/h15-17,22-29,32-33,36-38,40,51H,12-14,18-21H2,1-11H3/t25-,26-,27+,28+,29-,32+,33-,36-,37-,38?,40?,42-,43-/m1/s1
SMILES:CC[C@H]1[C@]2(C)[C@H]([C@H](C)C([C@H](C)(C[C@](C)(C([C@H](C)C([C@H](C)C(=O)O1)=O)OC1[C@H]([C@@H](C[C@@H](C)O1)N(C)C)O)OC))=O)N(CCCCn1cc(c3cccnc3)nc1)C(=O)O2

Properties:
Formula:C43H65N5O10Atoms:69
Molecular Weight:812.004Rotatable Bonds:11
H-bond Acceptors:13H-bond Donors:0
logP:4.8671
Targets:
Synonyms:
(1R,2R,4R,6R,7R,8R,10R,13R,14S)-7-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydro
11,12-Dideoxy-3-des(2,6-dideoxy-3-C,3-O-dimethyl-alpha-L-altropyranosyloxy)-6-O-methyl-3-oxo-12,11-(oxycarbonylimino)-N11-[4-[4-(3-pyridyl)imidazol-1-yl]butyl]erythromycin A
173838-31-8
173838-31-8 (DELETED)
191114-48-4
AC1MHE79
AIDS-086689
AIDS086689
CHEMBL1136
Erythromycin, 3-de((2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl)oxy)-11,12-dideoxy-6-O-methyl-3-oxo-12,11-(oxycarbonyl((4-(4-(3-pyridinyl)-1H-imidazol-1-yl)butyl)imino))-
Erythromycin, 3-de[(2,6-dideoxy-3-C-methyl-3-O-methyl-.alpha.-L-ribo-hexopyranosyl)oxy]-11,12-dideoxy-6-O-methyl-3-oxo-12,11-[oxycarbonyl[[4-[4-(3-pyridinyl)-1H-imidazol-1-yl]butyl]imino]]-
HMR 3647
HMR-3647
HMR3647
Ketek
Levviax
RU 66647
RU-66647
RU66647
TEL
Telithromycin
Telithromycin [INN:BAN]
UNII-KI8H7H19WL
Side-Effects:
Side-EffectFrequency
nausea0.059
diarrhea0.055875003
headache0.0395
dizziness0.02675
vertigo0.026749998
vomiting0.022250002
toxic epidermal necrolysis0.0010
allergic reactions0.0010
hepatic necrosis0.0010
hepatic failure0.0010
angioedema0.0010
arrhythmias0.0010
loss of consciousness0.0010
syncope0.0010
stevens johnson syndrome0.0010
pancreatitis0.0010
anaphylaxis0.0010
hepatitis0.0010
jaundice0.0010
muscle cramps0.0010
myasthenia gravis0.0010
edema0.0010
palpitations0.0010
liver function tests abnormal0
dyspepsia0
dysmenorrhea0
peripheral edema0
hyperkalemia0
colitis0
abdominal pain upper0
heart disease0
vascular disorders0
nervousness0
stomatitis0
ulcerative stomatitis0
paresthesia0
clotting0
constipation0
breast disorders0
anorexia0
thrombocythemia0
hypotension0
increased sweating0
anxiety0
insomnia0
abdominal pain0
abdominal distention0
neutropenia0
erythema multiforme0
connective tissue disorders0
somnolence0
fungal infection0
eosinophilia0
vaginitis0
polyuria0
disturbance in attention0
atopic dermatitis0
bundle branch block0
bradycardia0
eczema0
pain0
gastroesophageal reflux0
gastroenteritis0
anemia0
dry mouth0
urticaria0
pruritus0
reflux esophagitis0
drug hypersensitivity0
diplopia0
back pain0
hypokalemia0
flushing0
leukopenia0
eructation0
rash0
glossitis0
glossodynia0
mouth ulceration0
oral moniliasis0
asthenia0
fatigue0
nightmares0
alkaline phosphatase increased0
hypersensitivity0
flatulence0
vaginal moniliasis0
blurred vision0
gastritis0