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Drug Details

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Name:Enteropride
PubChem ID:2769
Pathway:Show KEGG pathways
InChI:InChI=1/C23H29ClFN3O4/c1-30-21-13-19(26)18(24)12-17(21)23(29)27-20-8-10-28(14-22(20)31-2)9-3-11-32-16-6-4-15(25)5-7-16/h4-7,12-13,20,22H,3,8-11,14,26H2,1-2H3,(H,27,29)/f/h27H
SMILES:COc1cc(c(cc1C(NC1CCN(CCCOc2ccc(cc2)F)CC1OC)=O)Cl)N

Properties:
Formula:C23H29ClFN3O4Atoms:32
Molecular Weight:465.945Rotatable Bonds:10
H-bond Acceptors:8H-bond Donors:0
logP:4.2681
Targets:
NameUniprot IDSourceReferencesInteraction
5-hydroxytryptamine (Serotonin) receptor 4Q546Q1_HUMANSuperTargetPMID 015355446shows
5-hydroxytryptamine 4 receptor isoform g2Q684M0_HUMANSuperTargetPMID 015355446shows
5-hydroxytryptamine 4 receptor subunit bQ8IXH9_HUMANSuperTargetPMID 015355446shows
5-hydroxytryptamine receptor 1F5HT1F_HUMANBindingDB-shows
5-hydroxytryptamine receptor 2A5HT2A_HUMANDrugBank-shows
5-hydroxytryptamine receptor 3A5HT3A_HUMANDrugBank-shows
5-hydroxytryptamine receptor 45HT4R_HUMANSuperTargetPMID 015355446shows
Alpha-1D adrenergic receptorADA1D_HUMANBindingDB-shows
Alpha-2C adrenergic receptorADA2C_HUMANBindingDB-shows
Beta-1 adrenergic receptorADRB1_HUMANBindingDB-shows
Beta-3 adrenergic receptorADRB3_HUMANBindingDB-shows
Cytochrome P450Q7Z448_HUMANSuperTargetPMID 015306208shows
Cytochrome P450Q86SK2_HUMANSuperTargetPMID 015306208shows
Cytochrome P450Q86SK3_HUMANSuperTargetPMID 015306208shows
Cytochrome P450 1A2CP1A2_HUMANSuperCyp-shows
Cytochrome P450 2A6CP2A6_HUMANSuperCypPMID 10780971shows
Cytochrome P450 2B6CP2B6_HUMANSuperCypPMID 10859153shows
Cytochrome P450 2C19CP2CJ_HUMANSuperCypPMID 10859153shows
Cytochrome P450 2C8CP2C8_HUMANSuperCypPMID 10859153shows
Cytochrome P450 2C9CP2C9_HUMANSuperCyp-shows
Cytochrome P450 2D6CP2D6_HUMANSuperCypPMID 10859153shows
Cytochrome P450 3A4CP3A4_HUMANSuperTargetPMID 015306208shows
Cytochrome P450 3A5CP3A5_HUMANSuperCypPMID 10780971shows
Cytochrome P450 3A7CP3A7_HUMANSuperCypPMID 10859153shows
Cytochrome P450 CYP3A4Q9BZM0_HUMANSuperTargetPMID 015306208shows
Cytochrome P450 family 3 subfamily A polypeptide 4Q6GRK0_HUMANSuperTargetPMID 015306208shows
D(1A) dopamine receptorDRD1_HUMANBindingDB-shows
D(2) dopamine receptorDRD2_HUMANBindingDB-shows
D(2) dopamine receptorDRD2_RATBindingDB-shows
Potassium channel HERGQ6U279_HUMANSuperTargetPMID 015967876shows
Potassium channel HERGQ6U283_HUMANSuperTargetPMID 015967876shows
Potassium channel HERGQ6U287_HUMANSuperTargetPMID 015967876shows
Potassium channel HERG1Q45QN5_HUMANSuperTargetPMID 015967876shows
Potassium voltage-gated channel subfamily H member 2KCNH2_HUMANSuperTargetPMID 015967876shows
Potassium voltage-gated channel, subfamily H (Eag-related), member 2Q708S9_HUMANSuperTargetPMID 015967876shows
Potassium voltage-gated channel, subfamily H (Eag-related), member 2Q86U57_HUMANSuperTargetPMID 015967876shows
Putative uncharacterized protein KCNH2Q75MK8_HUMANSuperTargetPMID 015967876shows
Putative uncharacterized protein KCNH2Q75MK9_HUMANSuperTargetPMID 015967876shows
Serotonin receptor 5-HT4Q712M9_HUMANSuperTargetPMID 015355446shows
Voltage-gated potassium channelQ45QN4_HUMANSuperTargetPMID 015967876shows
Synonyms:
(+-)-Cisapride
4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxypiperidin-4-yl]-2-methoxybenzamide
4-amino-5-chloro-N-[1-{3-[(4-fluorophenyl)oxy]propyl}-3-(methyloxy)piperidin-4-yl]-2-(methyloxy)benzamide
81098-60-4
86718-68-5
Acenalin
Acpulsif
Alimix
Alimix Forte
Alipride
Benzamide,
Benzamide, 4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxy -4-piperidinyl)-2-methoxy-, cis-
Benzamide, 4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinyl)-2-methoxy-, cis-
Benzamide, 4-amino-5-chloro-N-(1-(3-(4-fluorophenoxy)propyl)-3-methoxy-4-piperidinyl)-2-methoxy-, monohydrate, cis-
Benzamide, 4-amino-5-chloro-N-[1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidinyl]-2-methoxy-, cis-
C06910
C23H29ClFN3O4.H2O
Cipride
cis-4-Amino-5-chloro-N-(1-(3-(p-fluorophenoxy)propyl)-3-methoxy-4-piperidyl)-o-anisamide
Cisaprida
Cisaprida [INN-Spanish]
Cisaprida [Spanish]
Cisapride
Cisapride (USAN/INN)
CISAPRIDE MONOHYDRATE
Cisapride [USAN:BAN:INN:JAN]
Cisapridum
Cisapridum [INN-Latin]
Cisapridum [Latin]
Cisapron
Cisawal
Colinorm
D00274
DB00604
Dispep
EINECS 279-689-7
Enteropride
Esorid
Guptro
HSDB 3571
I01-0115
Kaudalit
Kinestase
LS-25437
NCGC00168465-01
Prepulsid
Presid
Prestwick0_000430
Prestwick1_000430
Prestwick2_000430
Prestwick_786
Pridesia
Propulsid
PROPULSID QUICKSOLV
Propulsin
Pulsid
R 51619
R-51619
Rapulid
Risamol
SPBio_002359
Syspride
T 1341
Unamol
Unipride
Vomiprid
Vomipride
ATC-Codes:
Side-Effects:
Side-EffectFrequency
headache0.193
allergic reaction0
upper respiratory tract infection0
tremor0
thrombocytopenia0
sinus tachycardia0
tachycardia0
suicide attempt0
sinusitis0
seizures0
rhinitis0
pruritus0
pharyngitis0
pancytopenia0
palpitations0
pain0
nervousness0
urinary incontinence0
urinary tract infection0
urticaria0
insomnia0
urinary frequency0
photosensitivity0
elevated liver enzymes0
parkinson0
galactorrhea0
myalgia0
migraine0
apathy0
dry mouth0
vomiting0
abnormal vision0
viral infection0
ventricular tachycardia0
ventricular fibrillation0
vaginitis0
nausea0
methemoglobinemia0
leukopenia0
constipation0
confusion0
chest pain0
bronchospasm0
back pain0
asthma0
arthralgia0
apnea0
anxiety0
angioedema0
hemolytic anemia0
aplastic anemia0
anemia0
amnesia0
agranulocytosis0
acidosis0
cough0
dehydration0
hypoglycemia0
breast enlargement0
hyperprolactinemia0
hyperglycemia0
hepatitis0
hallucinations0
gynecomastia0
flatulence0
fever0
fatigue0
rash0
edema0
dyspepsia0
somnolence0
dizziness0
diarrhea0
abdominal pain0