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Drug Details

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Name:Tomaxithen
PubChem ID:2733526
Pathway:Show KEGG pathways
InChI:InChI=1/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
SMILES:CC\C(c1ccccc1)=C(/c1ccccc1)c1ccc(cc1)OCCN(C)C

Properties:
Formula:C26H29NOAtoms:28
Molecular Weight:371.515Rotatable Bonds:8
H-bond Acceptors:2H-bond Donors:0
logP:5.9961
Targets:
NameUniprot IDSourceReferencesInteraction
Alternatively-spliced estrogen receptor alphaQ9Y2W8_HUMANSuperTargetPMID 016096456shows
Cytochrome P450Q6XP50_HUMANSuperTargetPMID 012769667shows
Cytochrome P450Q7Z448_HUMANSuperTargetPMID 012419838shows
Cytochrome P450Q86SK2_HUMANSuperTargetPMID 012419838shows
Cytochrome P450Q86SK3_HUMANSuperTargetPMID 012419838shows
Cytochrome P450 19A1CP19A_HUMANSuperCypPMID 10704911shows
Cytochrome P450 1A1CP1A1_HUMANSuperCypPMID 12124303shows
Cytochrome P450 1B1CP1B1_HUMANSuperCypPMID 11160641shows
Cytochrome P450 2A6CP2A6_HUMANSuperCypPMID 8293548shows
Cytochrome P450 2B6CP2B6_HUMANSuperCypPMID 16550168shows
Cytochrome P450 2C19CP2CJ_HUMANSuperCypPMID 16550168shows
Cytochrome P450 2C8CP2C8_HUMANSuperCypPMID 15601807shows
Cytochrome P450 2C9CP2C9_HUMANSuperCypPMID 17024799shows
Cytochrome P450 2D6CP2D6_HUMANSuperTargetPMID 012769667shows
Cytochrome P450 2E1CP2E1_HUMANSuperCypPMID 8293548shows
Cytochrome P450 3A4CP3A4_HUMANSuperTargetPMID 012419838shows
Cytochrome P450 3A5CP3A5_HUMANSuperCypPMID 15596297shows
Cytochrome P450 3A7CP3A7_HUMANSuperCyp-shows
Cytochrome P450 CYP3A4Q9BZM0_HUMANSuperTargetPMID 012419838shows
Cytochrome P450 family 3 subfamily A polypeptide 4Q6GRK0_HUMANSuperTargetPMID 012419838shows
Cytochrome P450, family 2, subfamily D, polypeptide 6Q6NWU0_HUMANSuperTargetPMID 012769667shows
Cytochrome P450db1Q16804_HUMANSuperTargetPMID 012769667shows
Epoxide hydrolase 2HYES_HUMANDrugBank-shows
Estrogen receptorESR1_HUMANSuperTargetPMID 016096456shows
Estrogen receptorQ9UBT1_HUMANSuperTargetPMID 016096456shows
Estrogen receptor 1Q9H2M1_HUMANSuperTargetPMID 016096456shows
Estrogen receptor 1Q9UE35_HUMANSuperTargetPMID 016096456shows
Estrogen receptor alphaQ9H2M2_HUMANSuperTargetPMID 016096456shows
Estrogen receptor betaESR2_HUMANSuperTargetPMID 16452668shows
Estrogen receptor-related protein proteinQ14268_HUMANSuperTargetPMID 016096456shows
Multidrug resistance protein 1MDR1_HUMANSuperTargetPMID 007841043shows
Multidrug resistance protein 1 variantQ59GY9_HUMANSuperTargetPMID 007841043shows
P-glycoproteinO60213_HUMANSuperTargetPMID 007841043shows
P-glycoprotein 1Q6TBL4_HUMANSuperTargetPMID 007841043shows
Putative uncharacterized protein DKFZp686N23123Q6MZQ9_HUMANSuperTargetPMID 016096456shows
Thymidine phosphorylaseTYPH_HUMANSuperTargetPMID 12016389shows
Synonyms:
(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine
(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (IUPAC)
(Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE
(Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
(Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine;
,citrate
1-p-.beta.-Dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
10540-29-1
1ya4
2-[4-[(Z)-1,2-di(phenyl)but-1-enyl]phenoxy]-N,N-dimethylethanamine
2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
54965-24-1
54965-24-1 (citrate)
AC1MBZ3R
AIDS-008877
AIDS008877
Ambap3115
BIDD:ER0008
BIDD:GT0009
BIDD:PXR0003
BPBio1_000278
BRD-K93754473-001-02-9
BRD-K93754473-048-05-3
BSPBio_000252
BSPBio_001150
BSPBio_001982
C07108
C26H29NO
CCG-205277
CCRIS 3275
CHEBI:41774
CHEMBL83
Citofen
cMAP_000044
Crisafeno
CTX
D08559
DB00675
Diemon
EINECS 234-118-0
Ethanamine, 2-(4-((1Z)-1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-
Ethanamine, 2-(4-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethyl-, (Z)-
Ethylamine, N,N-dimethyl-2-(p-(1,2-diphenyl-1-butenyl)phenoxy)-, (Z)-
Gen-Tamoxifen
HMS1362J11
HMS1792J11
HMS1990J11
HMS2090N08
HMS2232C12
HMS3261D09
HSDB 6782
ICI 46474 citrate
ICI 47699
ICI-46,474
ICI-46474
ICI-47699
IDI1_000258
IDI1_002170
Istubol
L024126
Lopac0_001203
LS-393
MLS001332535
MLS001332536
NCGC00024928-01
NCGC00024928-03
NCGC00024928-04
NCGC00024928-05
NCGC00024928-06
NCGC00024928-07
NCGC00024928-08
NCGC00024928-09
NCGC00024928-10
NCGC00024928-11
NCGC00024928-12
NCGC00024928-13
NCGC00024928-14
NCGC00024928-15
NCGC00024928-16
NCGC00024928-17
NCGC00024928-18
NCGC00024928-19
nchembio.140-comp7
nchembio.76-comp1
nchembio732-comp3
Nolvadex
Nolvadex-D
Nourytam
Novaldex
Novo-Tamoxifen
NSC 180973
NSC180973
NSC727681
OHT
Oncomox
Pms-Tamoxifen
Prestwick2_000146
Prestwick3_000146
QTL1_000079
Retaxim
SMR000059172
Soltamox
Spectrum5_001417
Spectrum5_002043
ST50511785
T5648_SIGMA
TAM
Tamizam
Tamone
Tamoplex (TN)
Tamoxen
Tamoxifen
Tamoxifen (INN)
TAMOXIFEN (TAMOXIFEN CITRATE (54965-24-1))
Tamoxifen (TN)
Tamoxifen (Z)
Tamoxifen and its salts
Tamoxifen citrate
Tamoxifen [INN:BAN]
Tamoxifene
Tamoxifene [INN-French]
Tamoxifeno
Tamoxifeno [INN-Spanish]
Tamoxifenum
Tamoxifenum [INN-Latin]
Tocris-0999
Tomaxithen
TRANS FORM OF TAMOXIFEN
trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
trans-Tamoxifen
UNII-094ZI81Y45
UPCMLD-DP027
Valodex
Zitazonium
ATC-Codes: