Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug Details

add
Name:Bisindolylmaleimide I
PubChem ID:2396
Pathway:Show KEGG pathways
InChI:InChI=1/C25H24N4O2/c1-28(2)12-7-13-29-15-19(17-9-4-6-11-21(17)29)23-22(24(30)27-25(23)31)18-14-26-20-10-5-3-8-16(18)20/h3-6,8-11,14-15,26H,7,12-13H2,1-2H3,(H,27,30,31)/f/h27H
SMILES:CN(C)CCCn1cc(c2ccccc12)C1=C(c2c[nH]c3ccccc23)C(NC1=O)=O

Properties:
Formula:C25H24N4O2Atoms:31
Molecular Weight:412.484Rotatable Bonds:6
H-bond Acceptors:5H-bond Donors:0
logP:3.9703
Targets:
NameUniprot IDSourceReferencesInteraction
3-phosphoinositide-dependent protein kinase 1PDPK1_HUMANBindingDB-shows
cAMP-dependent protein kinase catalytic subunit alphaKAPCA_RATBindingDB-shows
Cell division protein kinase 2CDK2_HUMANBindingDB-shows
Cell division protein kinase 4CDK4_HUMANBindingDB-shows
Glycogen synthase kinase-3 betaGSK3B_HUMANBindingDB-shows
Histamine H1 receptorHRH1_BOVINPROMISCUOUSPMID 9884076shows
Integrin-linked protein kinaseILK_CAVPOPROMISCUOUSPMID 7763256shows
Lethal factorLEF_BACANBindingDB-shows
Phosphatidylinositol 3-kinase alpha catalytic subunitQ91XL6_RATPROMISCUOUSPMID 14713290shows
Phosphatidylinositol 3-kinase catalytic subunit type 3PK3C3_HUMANPROMISCUOUSPMID 10710511shows
Phosphatidylinositol 3-kinase catalytic subunit type 3PK3C3_RATPROMISCUOUSPMID 14713290shows
Protein kinaseQ14495_HUMANPROMISCUOUSPMID 11841991shows
Protein kinaseQ15879_HUMANPROMISCUOUSPMID 11841991shows
Protein kinaseQ9H4D1_HUMANPROMISCUOUSPMID 11841991shows
Protein kinase cB8LXH5_TALSNPROMISCUOUSPMID 10381762shows
Protein kinase CKPC1_LYTPIPROMISCUOUSPMID 10381762shows
Protein kinase CKPC3_DROMEPROMISCUOUSPMID 10381762shows
Protein kinase C alpha typeKPCA_HUMANBindingDB-shows
Protein kinase C beta typeKPCB_HUMANBindingDB-shows
Protein kinase C epsilon typeKPCE_HUMANBindingDB-shows
Protein kinase C theta typeKPCT_HUMANBindingDB-shows
Proto-oncogene serine/threonine-protein kinase Pim-1PIM1_HUMANBindingDB-shows
Putative HERV-K_Xq28 provirus ancestral Pol proteinPOKL_HUMANPROMISCUOUSPMID 11642552shows
Serine/threonine-protein kinase D1KPCD1_HUMANPROMISCUOUSPMID 9973202shows
Sodium/potassium-transporting ATPase subunit alpha-1AT1A1_HUMANPROMISCUOUSPMID 15887250shows
Sodium/potassium-transporting ATPase subunit alpha-2AT1A2_HUMANPROMISCUOUSPMID 15887250shows
Sodium/potassium-transporting ATPase subunit alpha-3AT1A3_HUMANPROMISCUOUSPMID 15887250shows
Sodium/potassium-transporting ATPase subunit alpha-4AT1A4_HUMANPROMISCUOUSPMID 15887250shows
STE20-like serine/threonine-protein kinaseSLK_CAVPOPROMISCUOUSPMID 7763256shows
Telomerase reverse transcriptaseTERT_HUMANPROMISCUOUSPMID 11642552shows
Trans-sialidaseQ57XJ2_9TRYPPROMISCUOUSPMID 10527894shows
Synonyms:
"gö 6850"
"insolution™ bisindolylmaleimide i"
133052-90-1
1H-Pyrrole-2,5-dione,
1H-Pyrrole-2,5-dione, 3-(1-(3-(dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-
1uu8
1zrz
2-(1-(3-Dimethylaminopropyl)indol-3-yl)-3-(indol-3-yl)maleimide
2-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(1H-indol-3-yl)-maleimide
3-(1-(3-(Dimethylamino)propyl)-1H-indol-3-yl)-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione
3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE
6850
BI1
BIM-1
Bio2_000420
Bio2_000900
BiomolKI2_000039
BiomolKI_000031
BIS-1 cpd
Bisindolylmaleimide I
bisindoylmaleimide I
BSPBio_001160
C070515
C11238
C25H24N4O2
Gö 6850
GF 109203X
GF-109203X
GF109203X
GFX 203290
Go 6850
Go-6850
HSCI1_000290
IDI1_002175
IN1033
IN1518
IN1521
InSolution™ Bisindolylmaleimide I
KBio2_000500
KBio2_003068
KBio2_005636
KBio3_000919
KBio3_000920
KBioGR_000500
KBioSS_000500
LS-172856
NCGC00024760-01
NCGC00024760-02
NCGC00024760-03
NCGC00024760-04
nchembio.154-comp5
RBT205 INHIBITOR
Tocris-0741