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Drug Details

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Name:Neoperidole
PubChem ID:16362
Pathway:Show KEGG pathways
InChI:InChI=1/C28H29F2N3O/c29-22-11-7-20(8-12-22)25(21-9-13-23(30)14-10-21)4-3-17-32-18-15-24(16-19-32)33-27-6-2-1-5-26(27)31-28(33)34/h1-2,5-14,24-25H,3-4,15-19H2,(H,31,34)/f/h31H
SMILES:c1ccc2c(c1)[nH]c(n2C1CCN(CCCC(c2ccc(cc2)F)c2ccc(cc2)F)CC1)=O

Properties:
Formula:C28H29F2N3OAtoms:34
Molecular Weight:461.546Rotatable Bonds:7
H-bond Acceptors:5H-bond Donors:0
logP:5.7949
Targets:
NameUniprot IDSourceReferencesInteraction
5-hydroxytryptamine receptor 65HT6R_HUMANBindingDB-shows
CalmodulinCALM_HUMANDrugBank-shows
Cytochrome P450 1A2CP1A2_HUMANSuperCypPMID 9580580shows
Cytochrome P450 2C19CP2CJ_HUMANSuperCyp-shows
Cytochrome P450 2D6CP2D6_HUMANSuperCypPMID 9580580shows
Cytochrome P450 2E1CP2E1_HUMANSuperCyp-shows
Cytochrome P450 3A4CP3A4_HUMANBindingDB-shows
Cytochrome P450 3A5CP3A5_HUMANSuperCyp-shows
Cytochrome P450 3A7CP3A7_HUMANSuperCyp-shows
D(1A) dopamine receptorDRD1_HUMANSuperTarget-shows
D(1B) dopamine receptorDRD5_HUMANSuperTarget-shows
D(2) dopamine receptorDRD2_HUMANBindingDB-shows
D(3) dopamine receptorDRD3_HUMANSuperTarget-shows
D(4) dopamine receptorDRD4_HUMANSuperTarget-shows
Delta-type opioid receptorOPRD_HUMANBindingDB-shows
Kappa-type opioid receptorOPRK_HUMANBindingDB-shows
Mu-type opioid receptorOPRM_HUMANBindingDB-shows
Multidrug resistance protein 1MDR1_HUMANBindingDB-shows
Potassium voltage-gated channel subfamily H member 2KCNH2_HUMANBindingDB-shows
Voltage-dependent calcium channel gamma-1 subunitCCG1_HUMANSuperTarget-shows
Voltage-dependent L-type calcium channel subunit alpha-1CCAC1C_HUMANSuperTarget-shows
Voltage-dependent L-type calcium channel subunit alpha-1DCAC1D_HUMANSuperTarget-shows
Voltage-dependent L-type calcium channel subunit alpha-1FCAC1F_HUMANSuperTarget-shows
Voltage-dependent L-type calcium channel subunit alpha-1SCAC1S_HUMANSuperTarget-shows
Voltage-dependent L-type calcium channel subunit beta-1CACB1_HUMANSuperTarget-shows
Voltage-dependent L-type calcium channel subunit beta-3CACB3_HUMANSuperTarget-shows
Voltage-dependent L-type calcium channel subunit beta-4CACB4_HUMANSuperTarget-shows
Voltage-dependent T-type calcium channel subunit alpha-1GCAC1G_HUMANDrugBank-shows
Synonyms:
1-(1-(4,4-Bis(p-fluorophenyl)butyl)-4-piperidyl)-2-benzimidazolinone
1-(4,4-Bis(p-fluorophenyl)butyl)-4-(2-oxo-1-benzimidazolinyl)piperidine
1-[1-[4,4-bis(4-Fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-2H-benzimidazol-2-one
1-[1-[4,4-Bis(p-fluorophenyl)butyl]-4-piperidyl]-2-benzimidazolinone
1-[4,4-Bis(p-fluorophenyl)butyl]-4-(2-oxo-1-benzimidazolinyl)piperidine
1-{1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl}-1,3-dihydro-2H-benzimidazol-2-one
2-Benzimidazolinone, 1-(1-(4,4-bis(p-fluorophenyl)butyl)-4-piperidyl)-
2-Benzimidazolinone, 1-[1-[4,4-bis(p-fluorophenyl)butyl]-4-piperidyl]-
2062-78-4
2H-Benzimidazol-2-one,
2H-Benzimidazol-2-one, 1-(1-(4,4-bis(4-fluorophenyl)butyl)-4-piperidinyl)-1,3-dihydro-
2H-Benzimidazol-2-one, 1-[1-[4,4-bis(4-fluorophenyl)butyl]-4-piperidinyl]-1,3-dihydro-
3-[1-[4,4-bis(4-fluorophenyl)butyl]piperidin-4-yl]-1H-benzimidazol-2-one
5-24-02-00367 (Beilstein Handbook Reference)
AB00052215
Antalon
ASTA Medica Brand of Pimozide
BCBcMAP01_000043
BPBio1_000304
BRN 0729089
BSPBio_000276
BSPBio_001439
BSPBio_002941
C07566
C28H29F2N3O
CAS-2062-78-4
CCRIS 9172
CHEBI:8212
CID16362
D00560
D010868
DB01100
DivK1c_000386
EINECS 218-171-7
EU-0100946
Haldol decanoate
Halomonth
IDI1_000386
Janssen Brand of Pimozide
KBio1_000386
KBio2_000925
KBio2_003493
KBio2_006061
KBio3_002441
KBioGR_000720
KBioSS_000925
Lopac-P-1793
Lopac0_000946
LS-33236
McN-JR 6238
McN-JR-6238
MLS000028410
MLS001077311
NCGC00015802-01
NCGC00015802-02
NCGC00016601-01
NCGC00022282-03
NCGC00024888-01
NCGC00024888-02
NCGC00024888-03
NCGC00024888-04
NCGC00024888-05
NCGC00024888-06
NCGC00024888-07
NCIMech_000356
Neoperidole
NINDS_000386
NSC 170984
NSC170984
Opiran
Orap
Orap (TN)
Orap forte
P1793_SIGMA
Pharmascience Brand of Pimozide
Pimozide
Pimozide (JAN/USP/INN)
Pimozide [USAN:BAN:INN:JAN]
Pimozide [USAN:INN:BAN:JAN]
Pimozidum
Pimozidum [INN-Latin]
Prestwick0_000308
Prestwick1_000308
Prestwick2_000308
Prestwick3_000308
Prestwick_395
Primozida [INN-Spanish]
R 6238
R-6238
R6238
SMP1_000241
SMR000058385
SPBio_001211
SPBio_002495
SPECTRUM1501134
Spectrum2_001026
Spectrum3_001451
Spectrum4_000420
Spectrum5_001308
Spectrum_000445
Tocris-0937
WLN: T56 BMVNJ D- DT6NTJ A3YR DF&R DF
ATC-Codes:
Side-Effects:
Side-EffectFrequency
granulocytopenia0.0010
hypothermia0.0010
leukopenia0.0010
pancytopenia0.0010
pruritus0.0010
purpura0.0010
salivary hypersecretion0.0010
tremor0.0010
urticaria0.0010
ventricular fibrillation0.0010
ventricular tachycardia0.0010
dry mouth0.0010
urinary retention0.0010
electroencephalogram abnormal0.0010
galactorrhoea0.0010
blurred vision0.0010
tardive dyskinesia0.0010
hyperprolactinemia0.0010
hyperhidrosis0.0010
amenorrhoea0.0010
anemia0.0010
aplastic anemia0.0010
breast disorder0.0010
connective tissue disorders0.0010
constipation0.0010
dizziness0.0010
somnolence0.0010
endocrine disorder0.0010
eosinophilia0.0010
grand mal convulsion0.0010
rash0.0010
fecal incontinence0.0010
gynaecomastia0.0010
headache0.0010
cardiac disorders0.0010
insomnia0.0010