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Drug Details

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Name:Fosamprenavir
PubChem ID:131536
Pathway:Show KEGG pathways
InChI:InChI=1/C25H36N3O9PS/c1-18(2)15-28(39(33,34)22-10-8-20(26)9-11-22)16-24(37-38(30,31)32)23(14-19-6-4-3-5-7-19)27-25(29)36-21-12-13-35-17-21/h3-11,18,21,23-24H,12-17,26H2,1-2H3,(H,27,29)(H2,30,31,32)/t21-,23-,24+/m0/s1/f/h27,30-31H
SMILES:CC(C)CN(C[C@@H]([C@@H](Cc1ccccc1)NC(=O)O[C@H]1(CCOC1))OP(O)(O)=O)S(c1ccc(cc1)N)(=O)=O

Properties:
Formula:C25H36N3O9PSAtoms:42
Molecular Weight:585.607Rotatable Bonds:15
H-bond Acceptors:12H-bond Donors:0
logP:4.5727
Targets:
Synonyms:
((3S)Oxolan-3-yloxy)-N-((1S,2R)-3-{[(4-aminophenyl)sulfonyl](2-methylpropyl)amino}-1-benzyl-2-(phosphonooxy)propyl)carboxamide
(3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(ph
(3-(((4-Aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)carbamic acid C-(tetrahydro-3-furanyl) ester
226700-79-4
226700-80-7 (SODIUM SALT)
226700-81-8 (CALCIUM SALT)
AIDS-082186
AIDS082186
Amprenavir phosphate
Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-1-(phenylmethyl)-2-(phosphonooxy)propyl)-, C-((3S)-tetrahydro-3-furanyl) ester
D02497
DB01319
Fosamprenavir
Fosamprenavir (INN)
Fosamprenavir [INN]
GW 433908
GW433908
GW433908A (*Sodium Salt*)
GW433908G (*Calcium Salt*)
HSDB 7340
Lexiva (TM)
LS-187013
LS-187787
Telzir
VX 175
VX-175
[(3S)-oxolan-3-yl] N-[(2S,3R)-4-[(4-aminophenyl)sulfonyl-(2-methylpropyl)amino]-1-phenyl-3-phosphonooxybutan-2-yl]carbamate
ATC-Codes:
Side-Effects:
Side-EffectFrequency
diarrhea0.33375
nausea0.18249997
rash0.15
headache0.13714285
vomiting0.101249985
fatigue0.07
pruritus0.048333336
neutropenia0.043333333
abdominal pain0.04
paresthesia0.0325
mood disorders0.031999998
hypertriglyceridemia0.022499999
myalgia0
hyperglycemia0
hypercholesterolemia0
pain0
breast enlargement0
hiv infection0
diabetes mellitus0
stevens - johnson syndrome0
hemorrhage0
myositis0
flatulence0
drug hypersensitivity0
angioedema0
rhabdomyolysis0