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Drug Details

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Name:Tadalafil
PubChem ID:110635
Pathway:Show KEGG pathways
InChI:InChI=1/C22H19N3O4/c1-24-10-19(26)25-16(22(24)27)9-14-13-4-2-3-5-15(13)23-20(14)21(25)12-6-7-17-18(8-12)29-11-28-17/h2-8,16,21,23H,9-11H2,1H3/t16-,21-/m1/s1
SMILES:CN1CC(N2[C@H](Cc3c4ccccc4[nH]c3[C@@H]2(c2ccc3c(c2)OCO3))C1=O)=O

Properties:
Formula:C22H19N3O4Atoms:31
Molecular Weight:389.404Rotatable Bonds:1
H-bond Acceptors:5H-bond Donors:0
logP:2.0871
Targets:
Synonyms:
(6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-(methylenedioxy)phenyl) pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)py
(6R,12aR)-2,3,6,7,12,12a-Hexahydro-2-methyl-6-(3,4-methylenedioxyphenyl)pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R-trans)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione
(6R-trans)-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione
171596-29-5
1xoz
CIA
Cialis
Cialis (TN)
CPD000466321
D02008
DB00820
GF 196960
GF-196960
HSDB 7303
IC 351
IC-351
IC351
ICOS 351
KS-1117
LS-186558
LS-187015
LS-187770
MLS000759426
MLS001165782
MLS001195644
MLS001424132
Pyrazino(1',2':1,6)pyrido(3,4-b)indole-1,4-dione, 6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-, (6R,12aR)-
SAM001246586
SMR000466321
Tadalafil
Tadalafil (JAN/USAN/INN)
Tadalafil [USAN]
Tadanafil
ZINC03993855
ATC-Codes:
Side-Effects:
Side-EffectFrequency
headache0.10333333
dyspepsia0.057499997
back pain0.046666667
myalgia0.026666665
flushing0.020000001
pain in limb0.02
nasal congestion0.019999998
visual field defect0.0010
stevens - johnson syndrome0.0010
priapism0.0010
palpitations0.0010
stroke0.0010
retinal artery occlusion0.0010
sweating0.0010
loss of vision0.0010
neuropathy0.0010
blurred vision0.0010
migraine0.0010
decreased vision0.0010
urticaria0.0010
tachycardia0.0010
syncope0.0010
hearing loss0.0010
myocardial infarction0.0010
abdominal pain0.0010
angina pectoris0.0010
arrhythmia0.0010
transient ischemic attacks0.0010
chest pain0.0010
coronary artery disease0.0010
exfoliative dermatitis0.0010
diabetes0.0010
edema0.0010
nose bleed0.0010
hypotension0.0010
hypertension0.0010
hypersensitivity0.0010
hyperlipidemia0.0010
hyperhidrosis0.0010
gastroesophageal reflux0.0010
rash0.0010
liver function tests abnormal0
asthenia0
vertigo0
diarrhea0
tinnitus0
vomiting0
somnolence0
pain0
dysphagia0
nausea0
conjunctivitis0
arthralgia0
swelling0
postural hypotension0
fatigue0
paresthesia0
neck pain0
esophagitis0
insomnia0
pruritus0
dizziness0
abdominal pain upper0
eye pain0
dyspnea0
dry mouth0
pharyngitis0
gastritis0