Home
Drugs
Targets
Pathways
Ontologies
Cyp450s
Adv.search
Help/FAQ

Drug Details

add
Name:CHEMBL604712
PubChem ID:10429593
Pathway:Show KEGG pathways
InChI:InChI=1S/C19H22F2N4O2/c1-18(2,3)17(27)25-9-13-14(19(25,4)5)23-24-15(13)22-16(26)10-6-11(20)8-12(21)7-10/h6-8H,9H2,1-5H3,(H2,22,23,24,26)
SMILES:O=C(c1cc(F)cc(c1)F)Nc1n[nH]c2c1CN(C2(C)C)C(=O)C(C)(C)C

Properties:
Formula:C19H22F2N4O2Atoms:27
Molecular Weight:376.4Rotatable Bonds:5
H-bond Acceptors:5H-bond Donors:2
logP:3.5745
Targets:
NameUniprot IDSourceReferencesInteraction
Basic fibroblast growth factor receptor 1FGFR1_HUMANBindingDB-shows
cAMP-dependent protein kinase catalytic subunit alphaKAPCA_HUMANBindingDB-shows
Epidermal growth factor receptorEGFR_HUMANBindingDB-shows
FL cytokine receptorFLT3_HUMANBindingDB-shows
Glycogen synthase kinase-3 betaGSK3B_HUMANBindingDB-shows
Hepatocyte growth factor receptorMET_HUMANBindingDB-shows
High affinity nerve growth factor receptorNTRK1_HUMANBindingDB-shows
Inhibitor of nuclear factor kappa-B kinase subunit betaIKKB_HUMANBindingDB-shows
Insulin receptorINSR_HUMANBindingDB-shows
Insulin-like growth factor 1 receptorIGF1R_HUMANBindingDB-shows
MAP kinase-activated protein kinase 2MAPK2_HUMANBindingDB-shows
Mast/stem cell growth factor receptorKIT_HUMANBindingDB-shows
Mitogen-activated protein kinase 1MK01_HUMANBindingDB-shows
Mitogen-activated protein kinase 14MK14_HUMANBindingDB-shows
Protein kinase C alpha typeKPCA_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase ABL1ABL1_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase LCKLCK_HUMANBindingDB-shows
Proto-oncogene tyrosine-protein kinase receptor retRET_HUMANBindingDB-shows
RAC-alpha serine/threonine-protein kinaseAKT1_HUMANBindingDB-shows
Serine/threonine-protein kinase 6STK6_HUMANBindingDB-shows
Serine/threonine-protein kinase PLK1PLK1_HUMANBindingDB-shows
Tyrosine-protein kinase JAK2JAK2_HUMANBindingDB-shows
Vascular endothelial growth factor receptor 2VGFR2_HUMANBindingDB-shows
Vascular endothelial growth factor receptor 3VGFR3_HUMANBindingDB-shows
Synonyms:
CHEBI:696250
CHEMBL604712
CID 10429593
CID10429593